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一种糖基靶向的新方法:寡糖金属掩蔽的酶抑制作用。

A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding.

机构信息

Department of Chemistry, Virginia Commonwealth University, Richmond, Virginia 23284, USA.

出版信息

Chem Commun (Camb). 2014 Apr 21;50(31):4056-8. doi: 10.1039/c3cc49695c.

Abstract

Metalloglycomics - the effects of defined coordination compounds on oligosaccharides and their structure and function - opens new areas for bioinorganic chemistry and expands its systematic study to the third major class of biomolecules after DNA/RNA and proteins.

摘要

金属糖化学 - 定义明确的配位化合物对寡糖及其结构和功能的影响 - 为生物无机化学开辟了新的领域,并将其系统研究扩展到 DNA/RNA 和蛋白质之后的第三大类生物分子。

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