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三十年期间注意力缺陷多动障碍患病率估计:一项更新的系统评价和元回归分析

ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis.

作者信息

Polanczyk Guilherme V, Willcutt Erik G, Salum Giovanni A, Kieling Christian, Rohde Luis A

机构信息

Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil, Research Support Center on Neurodevelopment and Mental Health, University of São Paulo, São Paulo, Brazil, National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil, Department of Psychology and Neuroscience, University of Colorado at Boulder, Boulder, CO, USA and ADHD Outpatient Program at the Child and Adolescent Psychiatric Division, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

出版信息

Int J Epidemiol. 2014 Apr;43(2):434-42. doi: 10.1093/ije/dyt261. Epub 2014 Jan 24.

Abstract

BACKGROUND

Previous studies have identified significant variability in attention-deficit / hyperactivity disorder (ADHD) prevalence estimates worldwide, largely explained by methodological procedures. However, increasing rates of ADHD diagnosis and treatment throughout the past few decades have fuelled concerns about whether the true prevalence of the disorder has increased over time.

METHODS

We updated the two most comprehensive systematic reviews on ADHD prevalence available in the literature. Meta-regression analyses were conducted to test the effect of year of study in the context of both methodological variables that determined variability in ADHD prevalence (diagnostic criteria, impairment criterion and source of information), and the geographical location of studies.

RESULTS

We identified 154 original studies and included 135 in the multivariate analysis. Methodological procedures investigated were significantly associated with heterogeneity of studies. Geographical location and year of study were not associated with variability in ADHD prevalence estimates.

CONCLUSIONS

Confirming previous findings, variability in ADHD prevalence estimates is mostly explained by methodological characteristics of the studies. In the past three decades, there has been no evidence to suggest an increase in the number of children in the community who meet criteria for ADHD when standardized diagnostic procedures are followed.

摘要

背景

先前的研究已经确定,全球范围内注意力缺陷多动障碍(ADHD)患病率的估计存在显著差异,这在很大程度上可由方法学程序来解释。然而,在过去几十年中,ADHD诊断和治疗率的不断上升引发了人们对该疾病的真实患病率是否随时间增加的担忧。

方法

我们更新了文献中关于ADHD患病率的两项最全面的系统评价。进行了Meta回归分析,以检验在决定ADHD患病率差异的方法学变量(诊断标准、损害标准和信息来源)以及研究地理位置的背景下,研究年份的影响。

结果

我们识别出154项原始研究,并将135项纳入多变量分析。所研究的方法学程序与研究的异质性显著相关。地理位置和研究年份与ADHD患病率估计的差异无关。

结论

证实了先前的研究结果,ADHD患病率估计的差异主要由研究的方法学特征所解释。在过去三十年中,没有证据表明在遵循标准化诊断程序时,社区中符合ADHD标准的儿童数量有所增加。

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