Fuse H, Akakura K, Akimoto S, Shimazaki J
Department of Urology, School of Medicine, Chiba University.
Hinyokika Kiyo. 1987 Jul;33(7):1049-53.
Prostatic specific antigen (PA) level was determined with a Wako test kit (Japan) for prostatic cancer and others. The incidence of abnormal values of PA in untreated prostatic cancer, was 50, 50, 80, and 100% for stage A1, C (pN0, NX), D1 and D2 cancers, respectively. Grade was not related to the level of PA. Prostatic hypertrophy, prostatitis and urinary stone showed a false positive rate of 52, 18 and 0%, respectively. The level of PA was not correlated to those of prostatic acid phosphatase (RIA). In 31% of the cases, the elevated PA decreased 4 weeks after start of endocrine treatment. Elevated PA in low grade cancer was not normalized as much as that in high and moderate grade cancers. The positive rate of PA in the serum of reactivated patients was significantly higher than that of the patients with cancer under good control by endocrine treatment.
采用日本和光测试试剂盒测定前列腺特异性抗原（PA）水平，用于前列腺癌及其他疾病的检测。未经治疗的前列腺癌患者中，A1期、C期（pN0，NX）、D1期和D2期癌症患者PA异常值的发生率分别为50%、50%、80%和100%。分级与PA水平无关。前列腺肥大、前列腺炎和尿路结石的假阳性率分别为52%、18%和0%。PA水平与前列腺酸性磷酸酶（RIA）水平无关。31%的病例中，内分泌治疗开始4周后PA升高值下降。低级别癌症中PA升高值的恢复正常程度不如高级别和中级别癌症。复发患者血清中PA的阳性率显著高于内分泌治疗控制良好的癌症患者。
