Kubota T, Morimoto M, Kanaseki T, Inomata H
Third Department of Anatomy, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Brain Res. 1987 Sep 22;421(1-2):30-40. doi: 10.1016/0006-8993(87)91271-6.
To study the projection from the pretectum to the dorsal lateral geniculate nucleus (LGNd) in the cat, we used anterograde and retrograde transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP). Special attention was directed to the retinotopic maps of the pretectum and LGNd. Multiple restricted injections were made into different parts of the pretectum or LGNd. The pretectogeniculate pathway terminates mostly in the medial interlaminar nucleus (MIN) and layers A and A1, and to some extent in the lamina C within the ipsilateral LGNd. The lateral part of the nucleus of the optic tract (NTO) receives afferents from the superior retina, and the medial part of NTO and posterior pretectal nucleus (NPP) receives afferents from the inferior retina. There is no topographic organization in the retinal projection to the olivary pretectal nucleus (NOL). The lateral part of NTO projects ipsilaterally to the rostral portion of LGNd, which receives afferents from the superior retina. The medial part of NTO projects ipsilaterally to the caudal portion of LGNd, which receives afferents from the inferior retina. The NOL projects to all laminar parts of LGNd, ipsilaterally. The NPP projects largely to the ipsilateral MIN, which receives afferents from the pericentral and peripheral retina. These results suggest that similar parts of the retinotopic maps present in the pretectum and LGNd are connected.
为研究猫中顶盖前区向背外侧膝状体核（LGNd）的投射，我们使用了小麦胚凝集素 - 辣根过氧化物酶（WGA - HRP）的顺行和逆行运输。特别关注了顶盖前区和LGNd的视网膜拓扑图谱。在顶盖前区或LGNd的不同部位进行了多次局限性注射。顶盖前区 - 膝状体通路主要终止于内侧层间核（MIN）以及A层和A1层，在同侧LGNd的C层也有一定程度的终止。视束核（NTO）的外侧部分接收来自视网膜上半部分的传入纤维，NTO的内侧部分和顶盖前核后部（NPP）接收来自视网膜下半部分的传入纤维。视网膜向橄榄顶盖前核（NOL）的投射不存在拓扑组织。NTO的外侧部分同侧投射到LGNd的 Rostral 部分，该部分接收来自视网膜上半部分的传入纤维。NTO的内侧部分同侧投射到LGNd的尾侧部分，该部分接收来自视网膜下半部分的传入纤维。NOL同侧投射到LGNd的所有层状部分。NPP主要投射到同侧的MIN，MIN接收来自中央周围和周边视网膜的传入纤维。这些结果表明，顶盖前区和LGNd中存在的视网膜拓扑图谱的相似部分是相连的。
