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Cardiac calcium currents at the level of single channels.

作者信息

Tsien R W, Nilius B

机构信息

Department of Physiology, Yale University School of Medicine, New Haven, Connecticut 06510.

出版信息

Experientia. 1987 Dec 1;43(11-12):1169-72. doi: 10.1007/BF01945517.

DOI:10.1007/BF01945517
PMID:2446910
Abstract

Properties of cardiac Ca channels have come into sharper focus with the advent of single cell preparations and suction pipette recording methods. We briefly summarize our present picture of the gating and permeation properties of the conventional, dihydropyridine-sensitive type of Ca channel (L-type). Distinctive features of a second type of voltage-gated Ca channel (T-type) are discussed.

摘要

相似文献

1
Cardiac calcium currents at the level of single channels.
Experientia. 1987 Dec 1;43(11-12):1169-72. doi: 10.1007/BF01945517.
2
Studies on Ca channels in intact cardiac cells: voltage-dependent effects and cooperative interactions of dihydropyridine enantiomers.完整心肌细胞中钙通道的研究:二氢吡啶对映体的电压依赖性效应及协同相互作用
Mol Pharmacol. 1986 Dec;30(6):571-84.
3
A novel type of cardiac calcium channel in ventricular cells.心室细胞中一种新型的心脏钙通道。
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4
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Novel mechanism of voltage-dependent gating in L-type calcium channels.L型钙通道中电压依赖性门控的新机制。
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9
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10
Calcium channel types in cardiac myocytes: modulation by dihydropyridines and beta-adrenergic stimulation.心肌细胞中的钙通道类型:二氢吡啶类和β-肾上腺素能刺激的调节作用
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Dihydropyridine block of voltage-dependent K+ currents in rat dorsal root ganglion neurons.二氢吡啶对大鼠背根神经节神经元电压依赖性钾电流的阻断作用
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The use of calcium blockers to study biochemical behaviour of Saccharomyces cerevisiae cells.

本文引用的文献

1
The suction pipette method for internal perfusion and voltage clamp of small excitable cells.用于小的可兴奋细胞内部灌注和电压钳制的吸引移液管方法。
J Neurosci Methods. 1980 Feb;2(1):51-78. doi: 10.1016/0165-0270(80)90045-x.
2
Mechanism of ion permeation through calcium channels.离子通过钙通道的渗透机制。
Nature. 1984;309(5967):453-6. doi: 10.1038/309453a0.
3
Beta-adrenergic modulation of calcium channels in frog ventricular heart cells.蛙心室肌细胞中钙通道的β-肾上腺素能调节
Mol Cell Biochem. 2001 Dec;228(1-2):1-7. doi: 10.1023/a:1013327917724.
Nature. 1984;307(5949):371-5. doi: 10.1038/307371a0.
4
Elementary currents through Ca2+ channels in guinea pig myocytes.豚鼠心肌细胞中通过钙离子通道的基本电流。
Pflugers Arch. 1983 Sep;398(4):284-97. doi: 10.1007/BF00657238.
5
Ca2+ channel modulation by 8-bromocyclic AMP in cultured heart cells.8-溴环磷酸腺苷对培养心肌细胞中钙离子通道的调节作用
Nature. 1983;304(5925):462-4. doi: 10.1038/304462a0.
6
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells.维拉帕米、D600、地尔硫䓬和尼群地平在单个透析心脏细胞中对钙通道的阻滞机制
Nature. 1983 Apr 28;302(5911):790-4. doi: 10.1038/302790a0.
7
Effects of nystatin-mediated intracellular ion substitution on membrane currents in calf purkinje fibres.制霉菌素介导的细胞内离子置换对小牛浦肯野纤维膜电流的影响。
J Physiol. 1982 Aug;329:569-87. doi: 10.1113/jphysiol.1982.sp014320.
8
Block of outward current in cardiac Purkinje fibers by injection of quaternary ammonium ions.通过注射季铵离子来阻断心脏浦肯野纤维的外向电流。
J Gen Physiol. 1982 Jun;79(6):1041-63. doi: 10.1085/jgp.79.6.1041.
9
Properties of single calcium channels in cardiac cell culture.心脏细胞培养中单个钙通道的特性
Nature. 1982 Jun 10;297(5866):501-4. doi: 10.1038/297501a0.
10
Reversal of current through calcium channels in dialysed single heart cells.透析的单个心肌细胞中钙通道电流的反转
Nature. 1982 Jun 10;297(5866):498-501. doi: 10.1038/297498a0.