Toronto, Ontario, Canada Division of Plastic Surgery, Hospital for Sick Children, and the Department of Surgery, University of Toronto.
Plast Reconstr Surg. 2014 Feb;133(2):367-376. doi: 10.1097/01.prs.0000436852.32527.8a.
Congenital melanocytic nevi remain a subject of controversy with respect to risk of malignant transformation and recommended management. Recent studies indicate a lower malignant risk (0.7 to 2.9 percent) than had previously been estimated. Surgery has not been proven to reduce malignant risk or improve quality of life, and may result in undesirable aesthetic and functional outcomes. In this article, the authors review key controversial issues in the management of congenital melanocytic nevi and re-evaluate indications for surgical treatment. An updated review of controversial topics in the management of congenital melanocytic nevi is presented, and clinical applications are demonstrated through clinical cases. Updates regarding the risks and outcomes of congenital melanocytic nevi patients open a renewed debate with respect to the indications for surgery as well as the extent of surgery that may be suitable. Treatment should be tailored to achieve optimal aesthetic results whereby complete nevus excision is not the goal. As such, nonsurgical management and incomplete nevus excision should be integrated as legitimate parts of any treatment algorithm.
先天性黑素细胞痣在恶变风险和推荐治疗方面仍然存在争议。最近的研究表明,其恶变风险低于先前估计的(0.7%至2.9%)。手术并未被证明可以降低恶变风险或改善生活质量,反而可能导致不良的美学和功能结果。本文作者回顾了先天性黑素细胞痣治疗中存在争议的关键问题,并重新评估了手术治疗的适应证。通过临床病例展示了对先天性黑素细胞痣治疗中争议性话题的最新回顾,以及其临床应用。先天性黑素细胞痣患者的风险和结果的更新引发了关于手术适应证以及可能适合的手术范围的新一轮争论。治疗应根据最佳美学效果量身定制,而不是完全切除痣。因此,非手术治疗和不完全切除痣应作为任何治疗方案的合法部分。