Patel Nehal H, Sathvara Paresh, Patel Jigar, Vaghela Dipika
Department of Pediatrics, Gujarat Medical Education and Research Society Medical College, Sola, Ahmedabad, Gujarat, India.
J Pediatr Neurosci. 2013 Sep;8(3):228-31. doi: 10.4103/1817-1745.123687.
Intracranial tuberculomas continue to be a serious complication of central nervous system tuberculosis. Multiple central nervous system tuberculoma is commonly associated with human immunodeficiency virus (HIV) infection. The development of intracranial tuberculomas has been thought to be caused by hematogenous spread of tubercle bacilli on the surface of brain parenchyma from the primary site of infection. Here, we describe the case of a 5-year-old male child with severe protein energy malnutrition (Marasmus) having large cervical lymphadenopathy and severe nutritional rickets with deformity at presentation. The child developed convulsions 20 days after initiation of antituberculous drugs, and neuroimaging confirmed multiple miliary tuberculomas of brain as primary etiology for the convulsions.
颅内结核瘤仍然是中枢神经系统结核病的一种严重并发症。多发性中枢神经系统结核瘤通常与人类免疫缺陷病毒(HIV)感染有关。颅内结核瘤的形成被认为是结核杆菌从感染原发部位经血行播散至脑实质表面所致。在此,我们描述了一名5岁男童的病例,该患儿就诊时患有严重的蛋白质能量营养不良(消瘦症)、巨大颈部淋巴结病以及伴有畸形的严重营养性佝偻病。该患儿在开始抗结核药物治疗20天后出现惊厥,神经影像学检查证实脑部多发粟粒性结核瘤是惊厥的主要病因。