[卵巢鳞状细胞癌发展为皮样囊肿伴恶性转化的病例报告——免疫组织化学研究]

[A case report of ovarian squamous cell carcinoma developing into a dermoid cyst with malignant transformation--immunohistochemical study].

作者信息

Nakanishi Y, Nagai N, Shigemsa K, Myoga H, Egawa K, Tanaka T, Katsube Y, Nakagawa H, Fuziwara A

机构信息

Dept. of Obstet. & Gyne., Hiroshima Univ. School of Med.

出版信息

Gan No Rinsho. 1987 Nov;33(14):1860-5.

PMID:2447309

Abstract

A histopathological and immunohistochemical study has been made on a case of an ovarian cancer that developed into a dermoid cyst with a malignant transformation. The case involved a 64-year-old married woman and her clinical grading was determined as being in Stage Ia (i). The ovarian tumor, weighing 1550 g, consisted of large cystic and small solid parts, and a well-differentiated squamous cell carcinoma (large cell, keratinized type) was observed in the solid part. By using an immunoperoxidase technique (the ABC method), the SCC was found to be positive in many cancer cells and the TPA also was positive in some cancer cells, though both the CEA and AFP were found to be negative.

摘要

对一例发展为伴有恶性转化的皮样囊肿的卵巢癌病例进行了组织病理学和免疫组织化学研究。该病例为一名64岁已婚女性，临床分期确定为Ia（i）期。卵巢肿瘤重1550克，由大囊性和小实性部分组成，在实性部分观察到高分化鳞状细胞癌（大细胞，角化型）。通过免疫过氧化物酶技术（ABC法）发现，许多癌细胞中鳞状细胞癌（SCC）呈阳性，一些癌细胞中组织多肽抗原（TPA）也呈阳性，而癌胚抗原（CEA）和甲胎蛋白（AFP）均为阴性。