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当代长期护理实践中精神药物和认知增强药物的使用及其记录

Psychotropic and cognitive-enhancing medication use and its documentation in contemporary long-term care practice.

作者信息

Rojas-Fernandez Carlos, Mikhail Mina, Brown Susan G

机构信息

University of Waterloo School of Pharmacy, Kitchener, ON, Canada.

出版信息

Ann Pharmacother. 2014 Apr;48(4):438-46. doi: 10.1177/1060028013520196. Epub 2014 Jan 28.

Abstract

BACKGROUND

In long-term care (LTC) settings, use of psychotropic medications to manage behavioral and psychological symptoms of dementia and use of cognitive enhancers are commonplace. It is important that these medications are properly used to ensure resident well-being, and thus, it is paramount to understand use of these medications in contemporary practice to develop appropriate quality improvement initiatives.

OBJECTIVE

To characterize psychotropic and cognition-enhancing medication use LTC residents and current trends in documentation.

METHODS

Cross-sectional chart review of residents aged >65 years with dementia receiving psychotropic medications and/or cognitive enhancers.

RESULTS

From 180 residents, 84 (82% female) met inclusion criteria (average age 86 years). The prevalence of psychotropic medication use was as follows: cognitive enhancers, 71%; antidepressants, 98%; antipsychotics, 61%; sedative hypnotics, 23%. Quetiapine was the most commonly used antipsychotic (48%), followed by risperidone (28%) and olanzapine (15%), all of which were dosed within accepted guidelines. The duration of therapy ranged from 2 to 5 years for antipsychotic medications and 1¼ to 3 years for antidepressants. Documentation documentation rates were hightest for psychotropics versus cognitive enhancers. There was no documentation of attempts to lower doses or discontinue psychotropic medications or cognitive enhancers.

CONCLUSIONS

Many, but not all psychotropics used were acceptable choices. The duration of therapy appears to be excessive for antipsychotic medications. Documentation of ongoing need for medications varied and could be improved on to better assess residents' medication regimens. Further research will inform efforts to enhance the care of these residents.

摘要

背景

在长期护理(LTC)机构中,使用精神药物来管理痴呆症的行为和心理症状以及使用认知增强剂是很常见的。正确使用这些药物以确保居民的福祉非常重要,因此,了解这些药物在当代实践中的使用情况对于制定适当的质量改进措施至关重要。

目的

描述长期护理机构居民使用精神药物和认知增强剂的情况以及当前的记录趋势。

方法

对年龄大于65岁且正在接受精神药物和/或认知增强剂治疗的痴呆症居民进行横断面图表审查。

结果

在180名居民中,84名(82%为女性)符合纳入标准(平均年龄86岁)。精神药物的使用 prevalence如下:认知增强剂,71%;抗抑郁药,98%;抗精神病药,61%;镇静催眠药,23%。喹硫平是最常用的抗精神病药(48%),其次是利培酮(28%)和奥氮平(15%),所有这些药物的剂量均在公认的指南范围内。抗精神病药物的治疗持续时间为2至5年,抗抑郁药为1¼至3年。精神药物的记录率高于认知增强剂。没有关于尝试降低精神药物或认知增强剂剂量或停药的记录。

结论

许多(但不是所有)使用的精神药物是可接受的选择。抗精神病药物的治疗持续时间似乎过长。关于持续用药需求的记录各不相同,可以加以改进以更好地评估居民的用药方案。进一步的研究将为改善这些居民的护理工作提供信息。

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