Rojas-Fernandez Carlos, Dadfar Farzan, Wong Andrea, Brown Susan G
Schlegel Research Chair in Geriatric Pharmacotherapy, Schlegel-UW Research Institute for Ageing, School of Pharmacy, University of Waterloo, 10 Victoria St S, Room 7004, Kitchener, ON, N2G 1C5, Canada.
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BMC Res Notes. 2015 Oct 14;8:568. doi: 10.1186/s13104-015-1557-2.
Falls continue to be a problem for older people in long-term care (LTC) and retirement home (RH) settings and are associated with significant morbidity and health care use. Fall-risk increasing drugs (FRIDs) are known to increase fall risk and represent modifiable risk factors. There are limited data regarding the use of FRIDs in contemporary LTC and RH settings, and it has not been well documented to what extent medication regimens are reviewed and modified for those who have sustained falls. The objective of this study is to characterize medication related fall risk factors in LTC and RH residents and on-going use of medications known to increase fall risk.
Retrospective chart review of residents aged >65 who sustained one or more falls living in LTC or RH settings.
105 residents who fell one or more times during 2009-2010 were identified with a mean age of 89 years, a mean of nine scheduled medications and seven diagnoses, and 83% were women. Residents in LTC were ostensibly at higher risk for falls relative to those in RH settings as suggested by higher proportion of residents with multiple falls, multiple comorbidities, comorbidities that increase fall risk and visual impairment. Post fall injuries were sustained by 42% of residents, and residents in RH sustained more injuries relative to LTC residents (47 vs 34%). Use of FRIDs such as benzodiazepines, antipsychotic, antidepressant and various antihypertensive drugs was common in the present sample. No medication regimen changes were noted in the 6-month post fall period.
The present study documented common use FRIDs by LTC and RH residents with multiple falls. These potentially modifiable falls risk factors are not being adequately addressed in contemporary practice, demonstrating that there is much room for improvement with regards to the safe and appropriate use of medications in LTC and RH residents.
在长期护理(LTC)机构和养老院(RH)环境中,跌倒仍然是老年人面临的一个问题,并且与显著的发病率和医疗保健使用相关。已知增加跌倒风险的药物(FRIDs)会增加跌倒风险,是可改变的风险因素。关于当代LTC和RH环境中FRIDs使用的数据有限,对于跌倒者的药物治疗方案在何种程度上得到审查和修改也没有充分记录。本研究的目的是描述LTC和RH居民中与药物相关的跌倒风险因素以及已知会增加跌倒风险的药物的持续使用情况。
对居住在LTC或RH环境中发生一次或多次跌倒的65岁以上居民进行回顾性病历审查。
确定了105名在2009 - 2010年期间跌倒一次或多次的居民,平均年龄为89岁,平均有九种常规药物和七种诊断,83%为女性。与RH环境中的居民相比,LTC机构中的居民跌倒风险明显更高,这表现为多次跌倒、多种合并症、增加跌倒风险的合并症以及视力障碍的居民比例更高。42%的居民跌倒后受伤,与LTC居民相比,RH居民受伤更多(47%对34%)。在本样本中,苯二氮䓬类药物、抗精神病药物、抗抑郁药物和各种抗高血压药物等FRIDs的使用很常见。在跌倒后的6个月内未发现药物治疗方案有变化。
本研究记录了LTC和RH中多次跌倒居民对FRIDs的普遍使用情况。在当代实践中,这些潜在可改变的跌倒风险因素没有得到充分解决,这表明在LTC和RH居民安全、合理使用药物方面有很大的改进空间。