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表现为神经周围肉芽肿的类结节性副球孢子菌病

Sarcoid-like paracoccidioidomycosis presenting with perineural granuloma.

作者信息

Müller Silvia Ferreira Rodrigues, Miranda Mario Fernando Ribeiro de

机构信息

School of Medicine, Federal University of Pará, BelémPA, Brazil, PhD; Dermatologist. Assistant Professor of Dermatology, School of Medicine, Federal University of Pará (Universidade Federal do Pará - UFPA) - Belém (PA), Brazil.

School of Medicine, Federal University of Pará, BelémPA, Brazil, MD; Dermatologist; Board-certified Dermatopathologist - Assistant Professor of Dermatology, School of Medicine, Federal University of Pará (Universidade Federal do Pará - UFPA) - Belém (PA), Brazil.

出版信息

An Bras Dermatol. 2013 Nov-Dec;88(6):994-5. doi: 10.1590/abd1806-4841.20132309.

DOI:10.1590/abd1806-4841.20132309
PMID:24474116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3900358/
Abstract

Paracoccidioidomycosis presenting as a sarcoid-like plaque may be misdiagnosed as leprosy, especially when shared endemic areas are concerned. We report the case of a Brazilian male patient presenting with an ulcerated plaque on his left ear and neighboring areas. The plaque simulated tuberculoid leprosy type 1 reaction, both clinically and histopathologically. A perineural granuloma with no organisms detected by routine and Fite-Faraco staining reinforced that diagnosis. Paracoccidioidomycosis was confirmed only after a second biopsy, taken from the ulcerated area.

摘要

表现为结节病样斑块的副球孢子菌病可能会被误诊为麻风,尤其是在涉及共同流行地区时。我们报告了一例巴西男性患者,其左耳及邻近区域出现溃疡性斑块。该斑块在临床和组织病理学上均模拟了1型结核样麻风反应。常规和Fite-Faraco染色未检测到病原体的神经周围肉芽肿强化了该诊断。仅在从溃疡区域进行第二次活检后才确诊为副球孢子菌病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/e1b4f1f4b12e/abd-88-06-0994-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/fab370f998f2/abd-88-06-0994-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/9b3a4488de6e/abd-88-06-0994-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/aced48a8338f/abd-88-06-0994-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/e1b4f1f4b12e/abd-88-06-0994-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/fab370f998f2/abd-88-06-0994-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/9b3a4488de6e/abd-88-06-0994-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/aced48a8338f/abd-88-06-0994-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ec/3900358/e1b4f1f4b12e/abd-88-06-0994-g04.jpg

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引用本文的文献

1
Sarcoid-Like Paracoccidioidomycosis in a Female Urban Dweller: Reviewing a Rare Clinical Condition in Brazil.女性城市居民中的类肉瘤样球孢子菌病:巴西罕见临床疾病的综述。
Mycopathologia. 2018 Oct;183(5):847-852. doi: 10.1007/s11046-018-0266-5. Epub 2018 May 8.
2
A case of paracoccidioidomycosis due to presenting sarcoid-like form.一例呈现结节病样形态的副球孢子菌病病例。
Med Mycol Case Rep. 2017 Sep 25;19:6-8. doi: 10.1016/j.mmcr.2017.09.002. eCollection 2018 Mar.
3
Sarcoid-like cutaneous lesions in chronic adult paracoccidioidomycosis: report of two cases.

本文引用的文献

1
Paracoccidioidomycosis: sarcoid-like form in childhood.副球孢子菌病:儿童期的结节病样形式。
An Bras Dermatol. 2012 May-Jun;87(3):486-7. doi: 10.1590/s0365-05962012000300025.
2
Cutaneous perineural inflammation: a review.皮肤神经周围炎症:综述
J Cutan Pathol. 2010 Dec;37(12):1200-11. doi: 10.1111/j.1600-0560.2010.01614.x. Epub 2010 Aug 23.
3
Paracoccidioidomycosis: infiltrated, sarcoid-like cutaneous lesions misinterpreted as tuberculoid leprosy.副球孢子菌病:浸润性、类结节性皮肤病变被误诊为结核样麻风。
慢性成人副球孢子菌病中的结节病样皮肤病变:两例报告
Rev Inst Med Trop Sao Paulo. 2017 Jun 1;59:e36. doi: 10.1590/S1678-9946201759036.
Rev Inst Med Trop Sao Paulo. 2008 Jan-Feb;50(1):47-50. doi: 10.1590/s0036-46652008000100010.