癌胚抗原（CEA）、甲胎蛋白（AFP）、鳞状上皮细胞癌抗原（SP1）和人绒毛膜促性腺激素（HCG）作为卵巢癌肿瘤标志物的意义。
Significance of CEA, AFP, SP1 and HCG as tumor markers in ovarian carcinoma.
作者信息
Pulay T, Csömör S, Mészáros K, Szarka G, Csabay L, Szinnyai A
机构信息
1st Department of Gynecology and Obstetrics, Semmelweis Medical University, Budapest, Hungary.
出版信息
Neoplasma. 1987;34(5):595-600.
The significance of CEA, AFP, HCG and SP1 determinations in 85 patients with ovarian cancer were analyzed from the point of view of evaluation of the clinical status of the patients. On the basis of the trials it was stated that a satisfactory correlation between the extension of the tumor and the serum CEA level was observed in 26.6% of the cases. The efficiency of monitoring by systematic CEA tests was found to be 17.3%. The determination of AFP and HCG is useful only in cases of tumors with specific histological structures and in problems of differential diagnostics. The testing of SP1 is of no value in clinical practice.
从评估患者临床状况的角度分析了85例卵巢癌患者的癌胚抗原（CEA）、甲胎蛋白（AFP）、人绒毛膜促性腺激素（HCG）和妊娠相关血浆蛋白A（SP1）检测的意义。根据试验结果表明，在26.6%的病例中观察到肿瘤范围与血清CEA水平之间存在良好的相关性。通过系统性CEA检测进行监测的有效率为17.3%。AFP和HCG的检测仅在具有特定组织结构的肿瘤病例及鉴别诊断问题中有用。SP1检测在临床实践中没有价值。
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