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[一例产生甲胎蛋白、癌胚抗原及人绒毛膜促性腺激素的肾细胞癌]

[A case of alpha-fetoprotein, carcinoembryonic antigen and human chorionic gonadotropin producing renal cell carcinoma].

作者信息

Takakura N, Mimura H, Hamazaki K, Kim H, Hirata K, Miwata H, Kimura T, Sakata T, Hosoba T, Orita K

机构信息

1st Dept. of Surgery, Okayama Univ. Med. School.

出版信息

Gan No Rinsho. 1987 Sep;33(11):1385-90.

PMID:2444728
Abstract

A 51-year-old woman was admitted with a complaint of a left hypochondralgia and an abdominal mass. Laboratory testing showed a markedly increased alpha-fetoprotein (AFP) level (234,700 ng/ml). The enlargement of the left kidney and the adrenal gland was noted by CT scan and a tumorous thrombus was shown by inferior caval venography. The patient underwent a left nephrectomy, a combined resection of the spleen, tail of the pancreas and the removal of a tumorous caval thrombus. The patients AFP level gradually decreased after surgery. In a histological study, the tumor was diagnosed as a renal cell carcinoma and the presence of AFP, CEA, and HCG in the cancer cells was demonstrate by means of the "PAP" method.

摘要

一名51岁女性因左季肋部疼痛和腹部肿块入院。实验室检查显示甲胎蛋白(AFP)水平显著升高(234,700 ng/ml)。CT扫描发现左肾和肾上腺增大,下腔静脉造影显示有肿瘤性血栓。患者接受了左肾切除术、脾脏及胰尾联合切除术,并切除了肿瘤性腔静脉血栓。术后患者的AFP水平逐渐下降。组织学研究显示,肿瘤被诊断为肾细胞癌,采用“PAP”法证实癌细胞中存在AFP、CEA和HCG。

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