构建从生物途径到邻里环境的酒精相关结果中的种族差异。
Framing ethnic variations in alcohol outcomes from biological pathways to neighborhood context.
作者信息
Chartier Karen G, Scott Denise M, Wall Tamara L, Covault Jonathan, Karriker-Jaffe Katherine J, Mills Britain A, Luczak Susan E, Caetano Raul, Arroyo Judith A
机构信息
Virginia Commonwealth University School of Social Work , Richmond, Virginia.
出版信息
Alcohol Clin Exp Res. 2014 Mar;38(3):611-8. doi: 10.1111/acer.12304. Epub 2014 Jan 31.
Abstract
BACKGROUND
Health disparities research seeks to eliminate disproportionate negative health outcomes experienced in some racial/ethnic minority groups. This brief review presents findings on factors associated with drinking and alcohol-related problems in racial/ethnic groups.
METHODS
Those discussed are as follows: (i) biological pathways to alcohol problems, (ii) gene × stress interactions, (iii) neighborhood disadvantage, stress, and access to alcohol, and (iv) drinking cultures and contexts.
RESULTS
These factors and their interrelationships are complex, requiring a multilevel perspective.
CONCLUSIONS
The use of interdisciplinary teams and an epigenetic focus are suggested to move the research forward. The application of multilevel research to policy, prevention, and intervention programs may help prioritize combinations of the most promising intervention targets.
摘要
背景
健康差异研究旨在消除一些种族/族裔少数群体中不成比例的负面健康结果。本简要综述介绍了与种族/族裔群体饮酒及酒精相关问题相关因素的研究结果。
方法
所讨论的内容如下：（i）酒精问题的生物学途径，（ii）基因×应激相互作用，（iii）社区劣势、应激与酒精获取，以及（iv）饮酒文化与环境。
结果
这些因素及其相互关系很复杂，需要多层次的视角。
结论
建议采用跨学科团队并关注表观遗传学，以推动该研究向前发展。将多层次研究应用于政策、预防和干预项目，可能有助于确定最有前景的干预目标组合的优先级。
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