Infectious Diseases, VA Boston HCS, 1400 VFW Parkway, West Roxbury, MA 02312, USA; Infectious Diseases, Boston University School of Medicine, Dowling 3 North Room 3104, Boston, MA 02115, USA.
Section of Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Dowling 3 North Room 3104, Boston, MA 02115, USA.
Infect Dis Clin North Am. 2014 Mar;28(1):49-59. doi: 10.1016/j.idc.2013.10.002. Epub 2013 Dec 8.
Antibiotic resistance worsens clinical outcomes and, in some cases, significantly impacts the clinical management of urinary tract infections in the outpatient setting. This article presents the prevalence and mechanism of relevant antimicrobial resistance patterns encountered among uropathogens, and discusses the efficacy of antibiotic regimens and novel therapies in treating commonly encountered multidrug-resistant organisms.
抗生素耐药性会恶化临床结果,在某些情况下,还会显著影响门诊环境下尿路感染的临床管理。本文介绍了尿路病原体中常见的相关抗菌药物耐药模式的流行情况和机制,并讨论了治疗常见的多药耐药菌的抗生素方案和新疗法的疗效。