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紫穗槐的民族药理学、植物化学与药理学

Ethnopharmacology, phytochemistry and pharmacology of Tephrosia purpurea.

作者信息

Palbag Satadru, Dey Bijay Kr, Singh Narendra Kumar

机构信息

Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.

Bengal Institute of Pharmaceutical Sciences, SPLPIM Campus, Jadavpur University, W.B. 741235, India.

出版信息

Chin J Nat Med. 2014 Jan;12(1):1-7. doi: 10.1016/S1875-5364(14)60001-7.

DOI:10.1016/S1875-5364(14)60001-7
PMID:24484589
Abstract

Tephrosia purpurea (L.) Pers. is popularly known as 'Sarapunkha' in classical Ayurvedic texts. It is a perennial plant belonging to the family Fabaceae, and occurs throughout the Indian subcontinent. T. purpurea is traditionally used to treat splenomegaly, cirrhosis, cough and cold, abdominal swelling and as an antidote in the Ayurvedic system of medicine. Phytochemical investigations indicate the presence of semiglabrin, pongamole, lanceolatins A and B, rutin, lupeol, and β-sitosterol. Flavonoids including (+)-tephrorin A and B, (+)-tephrosone, an isoflavone, 7, 4'-dihydroxy-3', 5'-dimethoxyisoflavone and a chalcone, (+)-tephropurpurin were isolated from the whole plant. Pharmacological activities of different parts of the plant reported include anti-inflammatory, antiulcer, antimicrobial, antioxidant, antiallergic, antidiabetic, hepatoprotective, antitumor and insect repellent activity. In the present review, the literature on the phytochemical and pharmacological investigations of Tephrosia purpurea (L.) Pers. are summarized to August, 2012.

摘要

紫穗槐在经典阿育吠陀文献中俗称“萨罗蓬卡”。它是一种属于豆科的多年生植物,遍布印度次大陆。在阿育吠陀医学体系中,紫穗槐传统上用于治疗脾肿大、肝硬化、咳嗽和感冒、腹部肿胀以及用作解毒剂。植物化学研究表明其含有半光荚豆素、水黄皮素、披针叶黄檀素A和B、芦丁、羽扇豆醇和β-谷甾醇。从全株中分离出了黄酮类化合物,包括(+)-紫穗槐素A和B、(+)-紫穗槐酮、一种异黄酮、7,4'-二羟基-3',5'-二甲氧基异黄酮和一种查尔酮(+)-紫穗槐紫红素。据报道,该植物不同部位的药理活性包括抗炎、抗溃疡、抗菌、抗氧化、抗过敏、抗糖尿病、保肝、抗肿瘤和驱虫活性。在本综述中,截至2012年8月,对紫穗槐植物化学和药理研究的文献进行了总结。

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