新型射频设备在跳动心脏猪模型中心外膜消融性能。
Epicardial ablation performance of a novel radiofrequency device on the beating heart in pigs.
机构信息
Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, Missouri.
Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, Missouri.
出版信息
Ann Thorac Surg. 2014 Feb;97(2):673-8. doi: 10.1016/j.athoracsur.2013.10.036.
PURPOSE
Only bipolar clamps create reliable transmural lesions on the beating heart. This study evaluated the performance of a new radiofrequency (RF) device on the beating heart in an acute porcine model.
DESCRIPTION
Six domestic pigs were ablated with a novel bipolar RF linear device on the beating heart (ablation time of 40 s, 3 each on right and left atria and 1 each on superior and inferior vena cavae). The heart was stained with 2, 3, 5-triphenyl-tetrazolium chloride, and each lesion was cross-sectioned for lesion depth and transmurality.
EVALUATION
Transmurality was documented in 89% of the cross-sections. Sixty-three percent of lesions were transmural along the entire lesion length. Overall, 85% of the nontransmural cross-sections were located on the right atrium, and half of the nontransmural sections were in the superior or inferior vena cavae lesions.
CONCLUSIONS
This novel device was able to create transmural lesions on the beating heart, more effectively in the left atrium than in the right atrium.
目的
只有双极夹才能在跳动的心脏上产生可靠的贯穿壁损伤。本研究评估了一种新型射频（RF）设备在急性猪模型中跳动心脏上的性能。
描述
6 只家猪在跳动的心脏上使用新型双极 RF 线性设备进行消融（消融时间为 40 秒，右心房和左心房各 3 次，上腔静脉和下腔静脉各 1 次）。心脏用 2、3、5-三苯基氯化四氮唑染色，每个病变部位均进行切片以评估病变深度和贯穿性。
评估
在 89%的切片中记录到贯穿性。63%的病变在整个病变长度上是贯穿性的。总体而言，85%的非贯穿性切片位于右心房，而一半的非贯穿性切片位于上腔静脉或下腔静脉病变部位。
结论
这种新型设备能够在跳动的心脏上产生贯穿壁损伤，在左心房比在右心房更有效。
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