心脏海绵状血管瘤和多个肺海绵状血管瘤。

Cardiac cavernous hemangioma and multiple pulmonary cavernous hemangiomas.

机构信息

Institute of Pathology of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Ann Thorac Surg. 2014 Feb;97(2):687-9. doi: 10.1016/j.athoracsur.2013.05.111.

DOI:10.1016/j.athoracsur.2013.05.111

PMID:24484810

Abstract

We describe for the first time a rare coexistence of a cardiac cavernous hemangioma with multiple pulmonary cavernous hemangiomas. Computed tomography revealed bilateral pulmonary nodules, left pleural effusion, and pericardial effusion. Positron emission tomography showed a pericardial neoplasm. Pathologically, multiple large dilated vascular spaces, lined by a single layer of endothelial cells and filled with blood, were revealed in both the cardiac tumor and the pulmonary nodules. Immunohistochemical examination of the lining cells showed positivity for CD31, FLI1, FVIII, and CD34. Taken together, these findings led to the diagnosis of cardiac cavernous hemangioma and multiple pulmonary cavernous hemangiomas.

摘要

我们首次描述了心脏海绵状血管瘤与多个肺海绵状血管瘤的罕见共存。计算机断层扫描显示双侧肺结节、左侧胸腔积液和心包积液。正电子发射断层扫描显示心包肿瘤。病理检查显示心脏肿瘤和肺结节中均存在多个大的扩张血管腔，由单层内皮细胞衬里，充满血液。衬里细胞的免疫组织化学检查显示 CD31、FLI1、FVIII 和 CD34 阳性。综上所述，这些发现导致了心脏海绵状血管瘤和多个肺海绵状血管瘤的诊断。