Electrochemical synthesis of glycoconjugates from activated sterol derivatives.
作者信息
Tomkiel Aneta M, Kowalski Jan, Płoszyńska Jolanta, Siergiejczyk Leszek, Lotowski Zenon, Sobkowiak Andrzej, Morzycki Jacek W
机构信息
Institute of Chemistry, University of Białystok, Hurtowa 1, 15-399 Białystok, Poland.
Faculty of Chemistry, Rzeszów University of Technology, P.O. Box 85, 35-959 Rzeszów, Poland.
出版信息
Steroids. 2014 Apr;82:60-7. doi: 10.1016/j.steroids.2014.01.007. Epub 2014 Jan 30.
Several derivatives of cholesterol and other 3β-hydroxy-Δ(5)-steroids were prepared and tested as sterol donors in electrochemical reactions with sugar alcohols. The reactions afforded glycoconjugates with sugar linked to a steroid moiety by an ether bond. Readily available sterol diphenylphosphates yielding up to 54% of the desired glycoconjugate were found to be the best sterol donors.
Zotero 插件