Cabezalí Barbancho Daniel, Guerrero Ramos Felix, López Vázquez Francisco, Aransay Bramtot Adolfo, Gómez Fraile Andrés
*Division of Pediatric Urology †Department of Urology ‡Department of Pediatric Surgery, University Hospital, "12 de Octubre," Complutense University, Madrid, Spain.
Surg Laparosc Endosc Percutan Tech. 2014 Feb;24(1):22-5. doi: 10.1097/SLE.0b013e31829cebf1.
Traditionally, radical nephrectomy for Wilms tumor has been performed through an open approach. Advances in minimally invasive surgery have led to the application of these techniques to malignant lesions, including Wilms tumor. We aim to present our experience with laparoscopic nephrectomy (LN) for Wilms tumor.
Four patients with Wilms tumor were treated preoperatively with chemotherapy and afterwards underwent an LN and lymph node sampling. Four ports were placed and the tumors were removed without morcellation in an endoscopic bag through an incision by extending the umbilical or the suprapubic port site.
The average age at the time of surgery was 3 years and 7 months (range, 23 mo to 6 y). There were no intraoperative complications and the blood loss was minimal in all cases. The mean operative time was 125 minutes (range, 90 to 160 min). Among our patients, we had 2 stage IV and 2 stage I cases. The mean time of hospitalization was 3 days (range, 2 to 4 d). There were no long-term complications at the mean follow-up of 3 years and 6 months.
LN for Wilms tumor may be considered as an option in selected patients. Minimally invasive surgery allows the surgeon to follow all the oncologic principles required for surgical treatment of this neoplasm and provides the advantages of these techniques for cancer patients. Preoperative chemotherapy is essential to decrease tumor size and facilitate the dissection avoiding tumor rupture.
传统上,肾母细胞瘤的根治性肾切除术是通过开放手术进行的。微创手术的进展已导致这些技术应用于包括肾母细胞瘤在内的恶性病变。我们旨在介绍我们开展腹腔镜肾切除术(LN)治疗肾母细胞瘤的经验。
4例肾母细胞瘤患者术前接受化疗,随后接受LN及淋巴结采样。放置4个端口,通过延长脐部或耻骨上端口部位的切口,将肿瘤在内镜袋中完整切除,未进行粉碎。
手术时的平均年龄为3岁7个月(范围23个月至6岁)。所有病例均无术中并发症,失血极少。平均手术时间为125分钟(范围90至160分钟)。我们的患者中有2例IV期和2例I期病例。平均住院时间为3天(范围2至4天)。在平均3年6个月的随访中无长期并发症。
对于选定的患者,可考虑将LN作为肾母细胞瘤的一种治疗选择。微创手术使外科医生能够遵循该肿瘤手术治疗所需的所有肿瘤学原则,并为癌症患者提供这些技术的优势。术前化疗对于减小肿瘤大小和便于解剖以避免肿瘤破裂至关重要。