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驱动蛋白在快速轴突运输中的理论计算方法。

Theoretical calculation methods for kinesin in fast axonal transport.

作者信息

Chen Y, Hill T L

机构信息

Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892.

出版信息

Proc Natl Acad Sci U S A. 1988 Jan;85(2):431-5. doi: 10.1073/pnas.85.2.431.

Abstract

The method of making Monte Carlo calculations of the velocity of fast axonal transport is described and applied in a relatively simple case. These illustrative calculations are supplemented by a differential equation solution of the same problem, valid as an asymptotic limit. The latter treatment is closely related to the theory of muscle contraction.

摘要

描述了对快速轴突运输速度进行蒙特卡罗计算的方法,并将其应用于一个相对简单的案例中。这些示例计算辅以同一问题的微分方程解,该解作为渐近极限是有效的。后一种处理方法与肌肉收缩理论密切相关。

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本文引用的文献

1
Use of muscle contraction formalism for kinesin in fast axonal transport.
Proc Natl Acad Sci U S A. 1987 Jan;84(2):474-7. doi: 10.1073/pnas.84.2.474.
2
Kinetic diagram and free energy diagram for kinesin in microtubule-related motility.
Proc Natl Acad Sci U S A. 1986 May;83(10):3326-30. doi: 10.1073/pnas.83.10.3326.
3
Theoretical formalism for the sliding filament model of contraction of striated muscle. Part II.
Prog Biophys Mol Biol. 1975;29(2):105-59. doi: 10.1016/0079-6107(76)90021-3.

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