Arish Mohammad, Khallaghi Hoda, Soltani Elham, Akbarpour Reza
Zahedan University of Medical Sciences, Zahedan, Sistan and Baloochestan, Islamic Republic of Iran.
Int Ophthalmol. 2014 Oct;34(5):1055-9. doi: 10.1007/s10792-014-9908-x. Epub 2014 Feb 4.
The aim of this study was to compare the outcome and complications of sutureless trabeculectomy with conventional trabeculectomy. A total of 52 eyes were randomly assigned to two groups. One group received standard conventional trabeculectomy and the other group received sutureless trabeculectomy. The patients were evaluated at 1, 3, 6 and 12 months after surgery. Patient data such as sex, age, intraocular pressure (IOP), logMAR visual acuity, antiglaucoma medications, and intraoperative and postoperative complications were collected and statistically analyzed. The mean age of the conventional and sutureless groups was 48.5 ± 15.4 and 57.3 ± 13.9 years, respectively. All patients achieved IOP levels <21 mmHg with a mean IOP of 13.4 ± 5.3 mmHg in the conventional group and 12.8 ± 2.6 mmHg in the sutureless group at 6 months and 11.00 ± 1.3 and 12.4 ± 3.2 mmHg at 12 months post surgery, respectively. These results showed a significant decrease compared to preoperative measures but did not show a significant difference between the two groups (p = 0.659). The number of antigalucoma medications used postoperatively showed a significant decline from preoperative status of 0.7 ± 0.58 in the conventional group and 0.4 ± 0.4 in the sutureless trabeculectomy group after 6 months and 0.68 ± 0.8 and 0.78 ± 0.9 after 12 months, respectively; however, there was no significant difference between the two groups (p = 0.112). No intraoperative complications were encountered in any of the groups. One patient in the sutureless trabeculectomy group developed mild hyphema which was managed medically. In the conventional group, two patients had failed trabeculectomy which was successfully revised, two patients showed hypotony 2 days after surgery which was managed medically and normal pressure was achieved within 5 days. Sutureless trabeculectomy appears to be a safe and easy method with results comparable to conventional trabeculectomy.
本研究的目的是比较无缝线小梁切除术与传统小梁切除术的疗效及并发症。总共52只眼睛被随机分为两组。一组接受标准的传统小梁切除术,另一组接受无缝线小梁切除术。在术后1个月、3个月、6个月和12个月对患者进行评估。收集患者的性别、年龄、眼压(IOP)、logMAR视力、抗青光眼药物以及术中及术后并发症等数据,并进行统计学分析。传统组和无缝线组的平均年龄分别为48.5±15.4岁和57.3±13.9岁。所有患者术后6个月时眼压均<21 mmHg,传统组平均眼压为13.4±5.3 mmHg,无缝线组为12.8±2.6 mmHg;术后12个月时,传统组和无缝线组平均眼压分别为11.00±1.3 mmHg和12.4±3.2 mmHg。这些结果与术前测量值相比有显著下降,但两组之间无显著差异(p = 0.659)。术后使用抗青光眼药物的数量与术前相比有显著下降,传统组术后6个月时从术前的0.7±0.58降至0.4±0.4,术后12个月时降至0.68±0.8;无缝线小梁切除术组术后6个月时从术前的0.4±0.4降至0.78±0.9,术后12个月时降至0.78±0.9;然而,两组之间无显著差异(p = 0.112)。所有组术中均未出现并发症。无缝线小梁切除术组有1例患者出现轻度前房积血,经药物治疗。在传统组中,2例患者小梁切除术失败,经成功修复;2例患者术后2天出现低眼压,经药物治疗,5天内眼压恢复正常。无缝线小梁切除术似乎是一种安全简便的方法,其结果与传统小梁切除术相当。