Knecht H, Streuli R A, Odermatt B F, Rhyner K
Departement für Innere Medizin, Univeritätsspital, Zürich.
Schweiz Med Wochenschr. 1987 Dec 12;117(50):2038-41.
10 patients with diffuse large cell lymphoma were treated with 10 cycles of m-BACOD. 7 patients presented with a pathological stage IV, 2 with a clinical stage III and one with a clinical stage II disease. 8 patients have been in complete remission for 3-21 months (mean 9 months) after completion of therapy. One patient with T-immunoblastic lymphoma and bulky mass died of progressive disease after 6 cycles of m-BACOD. A second patient with T-immunoblastic lymphoma relapsed 24 months after completion of therapy. Treatment-related major complications, especially MTX-related ulcerative stomatitis, did not occur.
10例弥漫性大细胞淋巴瘤患者接受了10个周期的m-BACOD方案治疗。7例患者为病理IV期，2例为临床III期，1例为临床II期疾病。8例患者在完成治疗后已完全缓解3至21个月（平均9个月）。1例患有T免疫母细胞淋巴瘤且有巨大肿块的患者在接受6个周期的m-BACOD治疗后死于疾病进展。另1例T免疫母细胞淋巴瘤患者在完成治疗24个月后复发。未发生与治疗相关的主要并发症，尤其是与甲氨蝶呤相关的溃疡性口腔炎。
