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间日疟伴贫血、血小板减少、黄疸、肾脏损害及黑便的不典型表现:来自印度尼西亚非流行地区马朗的报告

Unusual presentation of vivax malaria with anaemia, thrombocytopenia, jaundice, renal disturbance, and melena: a report from malang, a nonendemic area in indonesia.

作者信息

Fitri Loeki Enggar, Sardjono Teguh Wahju, Hermansyah Bagus, Candradikusuma Didi, Berens-Riha Nicole

机构信息

Department of Parasitology, Faculty of Medicine, University of Brawijaya, Jalan Veteran Malang, East Java 65145, Indonesia.

Department of Parasitology, Faculty of Medicine, University of Jember, Jalan Kalimantan 37 Kampus Tegalboto, Jember East Java 68121, Indonesia.

出版信息

Case Rep Infect Dis. 2013;2013:686348. doi: 10.1155/2013/686348. Epub 2013 Dec 29.

Abstract

Most of the complications of malaria such as anaemia, thrombocytopenia, jaundice, and renal failure are commonly found in Plasmodium falciparum malaria, but the incidence of severe and complicated vivax malaria tends to be increasing. We report two cases of severe Plasmodium vivax malaria from Malang, a nonendemic area in Indonesia. Patients exhibited anaemia, thrombocytopenia, jaundice, renal disturbance, and melena. Microscopic peripheral blood examination and amplification of parasite 18s rRNA by polymerase chain reaction showed the presence of P. vivax and absence of P. falciparum. All patients responded well to antimalarial drugs.

摘要

疟疾的大多数并发症,如贫血、血小板减少、黄疸和肾衰竭,常见于恶性疟原虫疟疾,但重症和复杂的间日疟原虫疟疾的发病率呈上升趋势。我们报告了两例来自印度尼西亚非流行地区玛琅的重症间日疟原虫疟疾病例。患者表现出贫血、血小板减少、黄疸、肾脏功能紊乱和黑便。显微镜下外周血检查以及通过聚合酶链反应扩增寄生虫18s rRNA显示存在间日疟原虫而无恶性疟原虫。所有患者对抗疟药物反应良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15e8/3893748/7a7196a79a3e/CRIM.ID2013-686348.001.jpg

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