Thestrup-Pedersen K, Laurberg G, Søgaard H, Rønnevig J R
Department of Dermatology, Marselisborg Hospital, Aarhus C, Denmark.
Acta Derm Venereol. 1988;68(1):74-7.
Forty patients with psoriasis were investigated for unspecific and specific lymphocyte cytotoxicity in order to evaluate the significance for liver cell damage in methotrexate-treated (MTX) patients. We found no difference between psoriasis patients with regard to cytotoxicity. We also observed a normal proliferation of lymphocytes after stimulation with tuberculin and phytohemagglutinin.
为评估甲氨蝶呤(MTX)治疗的银屑病患者肝细胞损伤的意义,对40例银屑病患者的非特异性和特异性淋巴细胞细胞毒性进行了研究。我们发现银屑病患者之间在细胞毒性方面没有差异。在用结核菌素和植物血凝素刺激后,我们还观察到淋巴细胞的正常增殖。