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印度南部芒格洛尔市中枢神经系统脱髓鞘疾病的患病率及模式

Prevalence and patterns of demyelinating central nervous system disorders in urban Mangalore, South India.

作者信息

Pandit Lekha, Kundapur Rashmi

机构信息

KS Hegde Medical Academy, Nitte University, Mangalore, India

KS Hegde Medical Academy, Nitte University, Mangalore, India.

出版信息

Mult Scler. 2014 Oct;20(12):1651-3. doi: 10.1177/1352458514521503. Epub 2014 Feb 3.

DOI:10.1177/1352458514521503
PMID:24493471
Abstract

There is a dearth of epidemiological data about multiple sclerosis (MS) and related demyelinating disorders in India. In this study, a registry method was used for collecting data from secure sources and the index cases were verified Seventy nine patients were identified . A crude prevalence of 8.3/100,000 was obtained for MS and 6.2/100,000 for clinically-isolated syndrome (CIS). Age-standardized prevalence of MS relative to the world population was 7.8/100,000. Neuromyelitis optica (NMO) and spectrum disorders (NMOS) constituted 13.9% of all demyelinating disorders, with a prevalence of 2.6/100,000. Larger studies with more refined survey methodologies are required to understand the true prevalence of demyelinating disorders in India.

摘要

关于印度多发性硬化症(MS)及相关脱髓鞘疾病的流行病学数据匮乏。在本研究中,采用登记方法从可靠来源收集数据,并对索引病例进行了核实。共识别出79例患者。MS的粗患病率为8.3/10万,临床孤立综合征(CIS)的粗患病率为6.2/10万。相对于世界人口,MS的年龄标准化患病率为7.8/10万。视神经脊髓炎(NMO)及谱系疾病(NMOS)占所有脱髓鞘疾病的13.9%,患病率为2.6/10万。需要开展采用更精细调查方法的更大规模研究,以了解印度脱髓鞘疾病的真实患病率。

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