Tang Wen, Grace Blair, McDonald Stephen P, Hawley Carmel M, Badve Sunil V, Boudville Neil C, Brown Fiona G, Clayton Philip A, Johnson David W
Division of Nephrology, Peking University Third Hospital, Beijing, China ANZDATA Registry, Adelaide, Australia Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia.
ANZDATA Registry, Adelaide, Australia.
Perit Dial Int. 2015 Jul-Aug;35(4):450-9. doi: 10.3747/pdi.2013.00004. Epub 2014 Feb 4.
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The aim of the present study was to investigate the relationship between socio-economic status (SES) and peritoneal dialysis (PD)-related peritonitis. ♦
Associations between area SES and peritonitis risk and outcomes were examined in all non-indigenous patients who received PD in Australia between 1 October 2003 and 31 December 2010 (peritonitis outcomes). SES was assessed by deciles of postcode-based Australian Socio-Economic Indexes for Areas (SEIFA), including Index of Relative Socio-economic Disadvantage (IRSD), Index of Relative Socio-economic Advantage and Disadvantage (IRSAD), Index of Economic Resources (IER) and Index of Education and Occupation (IEO). ♦
7,417 patients were included in the present study. Mixed-effects Poisson regression demonstrated that incident rate ratios for peritonitis were generally lower in the higher SEIFA-based deciles compared with the reference (decile 1), although the reductions were only statistically significant in some deciles (IRSAD deciles 2 and 4 - 9; IRSD deciles 4 - 6; IER deciles 4 and 6; IEO deciles 3 and 6). Mixed-effects logistic regression showed that lower probabilities of hospitalization were predicted by relatively higher SES, and lower probabilities of peritonitis-associated death were predicted by less SES disadvantage status and greater access to economic resources. No association was observed between SES and the risks of peritonitis cure, catheter removal and permanent hemodialysis (HD) transfer. ♦
In Australia, where there is universal free healthcare, higher SES was associated with lower risks of peritonitis-associated hospitalization and death, and a lower risk of peritonitis in some categories.
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本研究旨在调查社会经济地位(SES)与腹膜透析(PD)相关腹膜炎之间的关系。♦
对2003年10月1日至2010年12月31日期间在澳大利亚接受PD治疗的所有非原住民患者,研究地区SES与腹膜炎风险及预后之间的关联(腹膜炎预后)。SES通过基于邮政编码的澳大利亚地区社会经济指数(SEIFA)十分位数进行评估,包括相对社会经济劣势指数(IRSD)、相对社会经济优势与劣势指数(IRSAD)、经济资源指数(IER)和教育与职业指数(IEO)。♦
本研究纳入7417例患者。混合效应泊松回归显示,与参照组(第一十分位数)相比,基于SEIFA的较高十分位数组中腹膜炎的发病率比值总体较低,尽管仅在某些十分位数组中有统计学显著降低(IRSAD十分位数组2和4 - 9;IRSD十分位数组4 - 6;IER十分位数组4和6;IEO十分位数组3和6)。混合效应逻辑回归表明,较高的SES预示住院概率较低,较低的社会经济劣势状态和更多的经济资源获取预示腹膜炎相关死亡概率较低。未观察到SES与腹膜炎治愈、导管拔除及永久性血液透析(HD)转换风险之间存在关联。♦
在澳大利亚,由于实行全民免费医疗保健,较高的SES与较低的腹膜炎相关住院和死亡风险以及某些类别中较低的腹膜炎风险相关。