Department of Renal Medicine, Nambour General Hospital, Nambour, Australia.
Nephrol Dial Transplant. 2012 May;27(5):2069-76. doi: 10.1093/ndt/gfr584. Epub 2011 Oct 9.
Australians living in rural regions have poorer health outcomes than city residents. This study compares rural and city patient access to and outcomes of renal replacement therapy (RRT) in Australia.
Non-indigenous Australians aged ≥16 years who commenced dialysis or underwent renal transplantation between 1996 and 2009 and were registered with the Australia and New Zealand Dialysis and Transplant Registry were included. Each patient's location was classified according to a remote area index as major city (MC), inner regional (IR), outer regional (OR) or remote/very remote (REM).
A total of 24 068 commenced dialysis and 5399 received a renal transplant during the study period. Patient distribution by remote area index was 71.3 and 70.8% MC, 19.1 and 18.6% IR, 8.4 and 9.1% OR and 1.1 and 1.5% REM for dialysis and transplant patients, respectively. RRT incidence per million population after adjusting for age and gender was 124 [95% confidence interval (CI): 122-126] MC, 106 (95% CI: 103-110) IR, 100 (95% CI: 96-105) OR and 96 (95% CI: 84-109) REM. After controlling for demographic variables, comorbidities and other covariates, hazard ratios for dialysis survival compared to MC were 1.08 (95% CI: 1.03-1.14) IR, 1.19 (95% CI: 1.11-1.28) OR and 1.03 (95% CI: 0.84-1.25) REM. Transplant patient survival was not statistically different by remoteness.
Rural Australians have lower incidence of RRT. Whether the causes of the lower RRT reflect lower disease rates or differential treatment access is not known. Differences in outcomes were seen for dialysis but not transplantation.
澳大利亚农村地区居民的健康状况不如城市居民。本研究比较了澳大利亚农村和城市地区患者接受肾脏替代治疗(RRT)的机会和结果。
1996 年至 2009 年间,年龄≥16 岁的非土著澳大利亚人开始透析或接受肾移植,并在澳大利亚和新西兰透析和移植登记处登记,包括在内。根据偏远地区指数,每位患者的位置被分类为主要城市(MC)、内区域(IR)、外区域(OR)或偏远/非常偏远(REM)。
在研究期间,共有 24068 人开始透析,5399 人接受肾移植。根据偏远地区指数,透析患者的分布分别为 71.3%和 70.8% MC、19.1%和 18.6% IR、8.4%和 9.1% OR 和 1.1%和 1.5% REM;移植患者的分布分别为 71.3%和 70.8% MC、19.1%和 18.6% IR、8.4%和 9.1% OR 和 1.1%和 1.5% REM。调整年龄和性别后,每百万人口的 RRT 发病率为 124[95%置信区间(CI):122-126] MC、106(95%CI:103-110)IR、100(95%CI:96-105)OR 和 96(95%CI:84-109)REM。在控制人口统计学变量、合并症和其他协变量后,与 MC 相比,透析患者生存的风险比为 1.08(95%CI:1.03-1.14)IR、1.19(95%CI:1.11-1.28)OR 和 1.03(95%CI:0.84-1.25)REM。移植患者的生存情况在偏远程度上没有统计学差异。
澳大利亚农村地区居民接受 RRT 的比例较低。较低的 RRT 是否反映了较低的疾病发病率或不同的治疗机会尚不清楚。透析患者的结果存在差异,但移植患者没有差异。