皮肤作为一个免疫器官。
The skin as an immunologic organ.
作者信息
Shimada S, Katz S I
机构信息
Dermatology Branch, National Cancer Institute, Bethesda, Md 20892.
出版信息
Arch Pathol Lab Med. 1988 Mar;112(3):231-4.
The epidermis is a heterogeneous tissue comprised of cells that may play a role in various types of immunologic responses. This review focuses on the importance of epidermal Langerhans' cells in antigen presenting and accessory cell functions, on the role of la-positive keratinocytes in generating certain types of immune responses, on the role of normal keratinocytes in the liberation of cytokines, on the identification of murine Thy-1-bearing dendritic epidermal cells, and on the modulation of epidermal immune functions by various physical and chemical agents.
表皮是一种异质性组织，由可能在各种免疫反应中发挥作用的细胞组成。本综述重点关注表皮朗格汉斯细胞在抗原呈递和辅助细胞功能中的重要性、la阳性角质形成细胞在产生某些类型免疫反应中的作用、正常角质形成细胞在细胞因子释放中的作用、小鼠含Thy-1树突状表皮细胞的鉴定，以及各种物理和化学因子对表皮免疫功能的调节。
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