Patafio Francis M, Mackillop William J, Feldman-Stewart Deb, Siemens David Robert, Booth Christopher M
Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.
Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.
Urol Oncol. 2014 May;32(4):391-5. doi: 10.1016/j.urolonc.2013.11.003. Epub 2014 Feb 6.
Despite clinical evidence and recommendations from international treatment guidelines, the use of perioperative chemotherapy for muscle-invasive bladder cancer in routine practice remains low. Although multiple studies have described underutilization, there is an urgent need to better understand the elements contributing to the observed gaps in care. In this commentary, we explore what is known about the factors contributing to underutilization of perioperative chemotherapy for muscle-invasive bladder cancer. We also propose a framework to guide future knowledge translation activities in an effort to improve the care and outcomes of patients with this disease.
尽管有临床证据以及国际治疗指南的推荐，但围手术期化疗在肌肉浸润性膀胱癌的常规治疗中的应用率仍然很低。虽然多项研究描述了其未得到充分利用的情况，但迫切需要更好地了解导致观察到的护理差距的因素。在本评论中，我们探讨了已知的导致肌肉浸润性膀胱癌围手术期化疗未得到充分利用的因素。我们还提出了一个框架，以指导未来的知识转化活动，努力改善这种疾病患者的护理和治疗结果。
