Trevisan M, Vaccaro O, Laurenzi M, De Chiara F, Di Muro M, Iacone R, Franzese A
Department of Social and Preventive Medicine, State University of New York at Buffalo 14214.
Hypertension. 1988 Mar;11(3):264-8. doi: 10.1161/01.hyp.11.3.264.
The present study was designed to investigate whether non-insulin-dependent diabetic hypertensive patients exhibit abnormalities in intracellular sodium metabolism similar to those described for essential hypertensive patients. Both normotensive and hypertensive non-insulin-dependent diabetic patients had similar average values of both Na+-Li+ countertransport and Na+-K+ cotransport compared with nondiabetic controls. Within the group of diabetic patients, hypertensive patients did not exhibit any abnormalities in either of the sodium transport pathways studied. The possible implications of these findings are addressed.
本研究旨在调查非胰岛素依赖型糖尿病高血压患者是否表现出与原发性高血压患者类似的细胞内钠代谢异常。与非糖尿病对照组相比，血压正常和高血压的非胰岛素依赖型糖尿病患者的钠-锂逆向转运和钠-钾协同转运的平均值相似。在糖尿病患者组中，高血压患者在所研究的任何一种钠转运途径中均未表现出任何异常。本文探讨了这些发现可能的意义。
