Division of Geriatric Medicine, University of Massachusetts Medical School, Worcester, Massachusetts; Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, Massachusetts; Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
J Am Geriatr Soc. 2014 Mar;62(3):518-24. doi: 10.1111/jgs.12684. Epub 2014 Feb 10.
To compare chart- and interview-based methods for identification of delirium.
Prospective cohort study.
Two academic medical centers.
Individuals aged 70 and older undergoing major elective surgery (N = 300) (majority orthopedic surgery).
Participants were interviewed daily during hospitalization for delirium using the Confusion Assessment Method (CAM; interview-based method), and their medical charts were reviewed for delirium using a validated chart-review method (chart-based method). Rate of agreement of the two methods and characteristics of those identified using each approach were examined. Predictive validity for clinical outcomes (length of stay, postoperative complications, discharge disposition) was compared. In the absence of a criterion standard, predictive value could not be calculated.
The cumulative incidence of delirium was 23% (n = 68) according to the interview-based method, 12% (n = 35) according to the chart-based method, and 27% (n = 82) according to the combined approach. Overall agreement was 80%; kappa was 0.30. The methods differed in detection of psychomotor features and time of onset. The chart-based method missed delirium in individuals that the CAM identified who were lacking features of psychomotor agitation or inappropriate behavior. The CAM-based method missed chart-identified cases occurring during the night shift. The combined method had high predictive validity for all clinical outcomes.
Interview- and chart-based methods have specific strengths for identification of delirium. A combined approach captures the largest number and broadest range of delirium cases.
比较基于图表和访谈的方法识别谵妄。
前瞻性队列研究。
两所学术医疗中心。
接受重大择期手术的 70 岁及以上个体(N=300)(多数为骨科手术)。
住院期间,使用意识混乱评估方法(CAM;访谈法)每天对患者进行谵妄访谈,使用经验证的图表审查方法(图表法)审查其病历以识别谵妄。检查两种方法的一致性,并研究每种方法识别的患者的特征。比较两种方法对临床结局(住院时间、术后并发症、出院去向)的预测有效性。由于没有金标准,因此无法计算预测值。
根据访谈法,谵妄的累积发生率为 23%(n=68),根据图表法为 12%(n=35),根据联合方法为 27%(n=82)。总体一致性为 80%;kappa 值为 0.30。两种方法在检测精神运动特征和发病时间方面存在差异。图表法漏诊了 CAM 识别的但缺乏精神运动兴奋或行为不当特征的患者的谵妄。CAM 法漏诊了夜间发生的、被图表法识别的病例。联合方法对所有临床结局均具有较高的预测有效性。
基于访谈和图表的方法在识别谵妄方面各有优势。联合方法可以捕捉到数量最多、范围最广的谵妄病例。