Palakurthy P R, Slater D
Department of Medicine, University of Louisville School of Medicine, Kentucky.
Pacing Clin Electrophysiol. 1988 Feb;11(2):185-92. doi: 10.1111/j.1540-8159.1988.tb04540.x.
Ninety patients (13 patients with supraventricular tachycardia and 72 patients with ventricular tachycardia) underwent electrophysiological study. Six out of 18 patients with supraventricular tachycardia (33%) and one out of 72 patients with ventricular tachycardia (1.4%) were considered suitable candidates for the scanning pacemaker. However, only six of the seven patients underwent implantation. The seventh patient decided not to undergo implantation and continued to have recurrent episodes of supraventricular tachycardia. The scanning pacemaker delivers extrastimuli at preset initial and coupled delay after four cycles of tachycardia. If tachycardia is not terminated, another set of extrastimuli are delivered with a decrement in the coupling cycle. During the follow-up period of 7-25 months (mean, 14.3 months), tachycardia cycle lengths and termination windows changed in four patients. The pacemakers in these patients were reprogrammed multiple times (2 to 6 times with a mean of 3.5) as the previous number of extrastimuli and intervals were ineffective in the termination of tachycardias. The major limitations of the extrastimulus pacemaker were: 1) only a small percentage of patients were suitable candidates for its use; (2) the initially selected termination window in the majority of patients was ineffective during the follow-up period due mainly to the changes in tachycardia cycle length and subsequent termination windows; and (3) the majority (five out of six patients in this series) of patients needed additional pharmacologic therapy to modify their tachycardia rates. However, despite these limitations, the scanning pacemaker may be an additional tool in the management of recurrent tachyarrhythmias in selected patients.
90例患者(13例室上性心动过速患者和72例室性心动过速患者)接受了电生理研究。18例室上性心动过速患者中有6例(33%)和72例室性心动过速患者中有1例(1.4%)被认为是扫描起搏器的合适候选者。然而,7例患者中只有6例接受了植入。第7例患者决定不接受植入,继续有室上性心动过速的反复发作。扫描起搏器在心动过速4个周期后,按预设的初始和耦合延迟发放额外刺激。如果心动过速未终止,则以耦合周期递减的方式发放另一组额外刺激。在7至25个月(平均14.3个月)的随访期内,4例患者的心动过速周期长度和终止窗口发生了变化。由于之前的额外刺激数量和间期在终止心动过速方面无效,这些患者的起搏器被多次重新编程(2至6次,平均3.5次)。额外刺激起搏器的主要局限性为:1)只有一小部分患者适合使用;(2)大多数患者最初选择的终止窗口在随访期内无效,主要原因是心动过速周期长度和随后的终止窗口发生了变化;(3)大多数患者(本系列6例患者中的5例)需要额外的药物治疗来调整其心动过速速率。然而,尽管有这些局限性,扫描起搏器可能是选定患者复发性快速性心律失常管理中的一种辅助工具。