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冠状动脉-大隐静脉复合移植血管的评估:主动脉非接触技术

Evaluation of coronary artery-saphenous vein composite grafts: the aortic no-touch technique.

作者信息

Coskun Isa, Colkesen Yucel, Demirturk Orhan Saim, Tunel Huseyin Ali, Turkoz Riza, Gulcan Oner

机构信息

Departments of Cardiovascular Surgery (Drs. Coskun, Demirturk, Gulkan, Tunel, and Turkoz) and Cardiology (Dr. Colkesen), Baskent University, 01250 Adana, Turkey.

出版信息

Tex Heart Inst J. 2014 Feb;41(1):26-32. doi: 10.14503/THIJ-13-3154.

Abstract

We retrospectively compared the results of conventional coronary artery bypass grafting (CABG) performed on patients who showed no preoperative evidence of serious atherosclerosis of the ascending aorta with the results of the aortic no-touch technique (using coronary artery-saphenous vein composite grafts) on CABG patients who did show such evidence. From 2003 through 2012, 3,152 consecutive patients underwent isolated primary CABG at our hospital. We chose 360 for the current study. The study group (n=120) comprised patients who had undergone operation via the aortic no-touch technique. Propensity-score-matching (1:2) was used to select the control group of 240 patients who had undergone conventional CABG. Early and late survival rates, reintervention-free survival rates, and freedom from cardiac death were compared. Early and late mortality rates were similar in the study and control groups (P=0.19 vs P=0.29, respectively), as were cardiac-related death (2.5% vs 2.1%, respectively; P=0.53) and overall death (8.3% vs 7.9%, respectively; P=0.51). Overall survival rates were 91.7% vs 92.1% and freedom-from-cardiac-death rates were 97.4% vs 97.5% (P=0.71 vs P=0.78, respectively; mean follow-up period, 5.27 ± 2.51 yr). Reintervention-free survival rates were also similar (96.7% vs 98.8%, respectively; P=0.2). As a result of the similar rates of early and late survival, reintervention-free survival, and freedom from cardiac death, we conclude that the aortic no-touch technique with composite grafts might be a reasonable option in patients who have atherosclerotic ascending aorta that cannot be clamped.

摘要

我们回顾性比较了在升主动脉无严重动脉粥样硬化术前证据的患者中进行传统冠状动脉旁路移植术(CABG)的结果,以及在有此类证据的CABG患者中采用主动脉非接触技术(使用冠状动脉 - 大隐静脉复合移植物)的结果。2003年至2012年期间,我院连续3152例患者接受了单纯初次CABG。我们选择了360例进行本研究。研究组(n = 120)包括通过主动脉非接触技术接受手术的患者。采用倾向得分匹配(1:2)选择240例接受传统CABG的患者作为对照组。比较了早期和晚期生存率、无再次干预生存率以及无心脏死亡情况。研究组和对照组的早期和晚期死亡率相似(分别为P = 0.19和P = 0.29),心脏相关死亡率(分别为2.5%和2.1%;P = 0.53)和总死亡率(分别为8.3%和7.9%;P = 0.51)也相似。总体生存率分别为91.7%和92.1%,无心脏死亡生存率分别为97.4%和97.5%(分别为P = 0.71和P = 0.78;平均随访期为5.27±2.51年)。无再次干预生存率也相似(分别为96.7%和98.8%;P = 0.2)。由于早期和晚期生存率、无再次干预生存率以及无心脏死亡的发生率相似,我们得出结论,对于无法夹闭的动脉粥样硬化性升主动脉患者,采用复合移植物的主动脉非接触技术可能是一种合理的选择。

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