Milandre L, Gueriot C, Valli M
Clinique Neurologique, CHU Timone, Marseille.
Schweiz Arch Neurol Psychiatr (1985). 1988;139(1):17-30.
Brain ischemia induces an original form of edema associating a "cytotoxic" component and a "vasogenic" component which is more inconstant. The authors set out a synthesis of fundamental research concerning the different factors of ischemic brain edema. Although anti-edematous drugs (steroids, barbiturates, diuretics) are widely used, there is no serious evidence of their efficacity. New therapies are based on a specific approach of the different disturbances of cerebral ischemia. However, controlled studies are necessary to evaluate the effects of these new drugs.
