Herzog J, Schmidt B, Fassbender T, Hübener K H
Medizinisches Strahleninstitut, Universität Tübingen.
Strahlenther Onkol. 1988 Mar;164(3):121-8.
A retrospective study was conducted on 67 patients irradiated between 1976 and 1983 at the Medical Radiologic Institute of Tübingen for local recurrences of primarily operated carcinomas of the rectum. Generally, a total dose of 50 to 60 Gy was applied partially in form of a rotational therapy with individual doses of 2 Gy each. The irradiation was well tolerated by most of the patients. The troubles which were mostly severe and progressive before radiotherapy could be relieved by the irradiations in 91% of the patients. This palliative effect lasted for twelve months on an average. The prognosis quoad vitam is unfavorable with a median survival time of 21 months and a three-year survival rate of 15%. A clear dependence on the dose was not found for any of these parameters. Our own results are compared to those communicated by other authors. It is shown that better results can only be achieved by re-operation performed in sano.
对1976年至1983年间在图宾根医学放射研究所接受放疗的67例直肠癌初次手术后局部复发患者进行了回顾性研究。一般来说,总剂量为50至60 Gy,部分采用旋转治疗,每次剂量为2 Gy。大多数患者对放疗耐受性良好。放疗前大多严重且呈进行性的问题在91%的患者中通过放疗得到缓解。这种姑息效果平均持续12个月。生存预后不佳,中位生存时间为21个月,三年生存率为15%。未发现这些参数中的任何一个与剂量有明显相关性。将我们自己的结果与其他作者报告的结果进行了比较。结果表明,只有通过根治性再次手术才能取得更好的效果。