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澳大利亚成年人群样本中白天过度嗜睡的患病率。

Prevalence of excessive daytime sleepiness in a sample of the Australian adult population.

作者信息

Hayley Amie C, Williams Lana J, Kennedy Gerard A, Berk Michael, Brennan Sharon L, Pasco Julie A

机构信息

School of Medicine, Deakin University, Geelong, Australia.

School of Medicine, Deakin University, Geelong, Australia; Department of Psychiatry, The University of Melbourne, Parkville, Australia.

出版信息

Sleep Med. 2014 Mar;15(3):348-54. doi: 10.1016/j.sleep.2013.11.783. Epub 2014 Jan 18.

DOI:10.1016/j.sleep.2013.11.783
PMID:24513435
Abstract

OBJECTIVES

Excessive daytime sleepiness (EDS) is associated with significant personal and medical burden. However, there is little indication of the impact of these symptoms in the broader population.

PARTICIPANTS AND METHODS

We studied 946 men ages 24-92 years (median age, 59.4 [interquartile range {IQR}, 45-73 years]) and 1104 women ages 20-94 years (median age, 50 [IQR, 34-65 years]) who resided in the Barwon Statistical Division, South-Eastern Australia, and participated in the Geelong Osteoporosis Study (GOS) between the years of 2001 and 2008. EDS was defined as an Epworth Sleepiness Scale (ESS) score of ⩾ 10. Lifestyle factors, history of medical conditions, and medication history were documented by self-report.

RESULTS

For men, the age-specific prevalence of EDS was 5.1% (ages 20-29 years), 6.4% (ages 30-39 years), 9.8% (ages 40-49 years), 15.5% (ages 50-59 years), 12.0% (ages 60-69 years), 12.0% (ages 70-79 years), and 29.0% (ages ⩾ 80 years). For women, the age-specific prevalence of EDS was 14.7% (ages 20-29 years), 8.7% (ages 30-39 years), 15.0% (ages 40-49 years), 16.0% (ages 50-59 years), 12.6% (ages 60-69 years), 13.2% (ages 70-79 years), and 17.0% (ages ⩾ 80 years). Overall standardized prevalence of EDS was 10.4% (95% confidence interval, 9.7-11.2) for men and 13.6% (95% confidence interval, 12.8-14.4) for women.

CONCLUSIONS

The prevalence of EDS increased with age, affecting approximately one-third of those aged ⩾ 80 years. Because EDS has been associated with poorer health outcomes in the older age strata, these findings suggest that routine screening may be beneficial in ongoing health assessments for these individuals. Overall, more than one-tenth of the Australian adult population has EDS, which is indicative of possible underlying sleep pathology.

摘要

目的

日间过度嗜睡(EDS)会带来重大的个人和医疗负担。然而,几乎没有迹象表明这些症状对更广泛人群的影响。

参与者与方法

我们研究了居住在澳大利亚东南部巴尔温统计区、于2001年至2008年期间参与吉朗骨质疏松症研究(GOS)的946名年龄在24至92岁(中位年龄59.4岁[四分位间距{IQR},45 - 73岁])的男性以及1104名年龄在20至94岁(中位年龄50岁[IQR,34 - 65岁])的女性。EDS被定义为爱泼沃斯嗜睡量表(ESS)得分≥10分。生活方式因素、病史和用药史通过自我报告记录。

结果

男性中,EDS的年龄特异性患病率在20 - 29岁为5.1%,30 - 39岁为6.4%,40 - 49岁为9.8%,50 - 59岁为15.5%,60 - 69岁为12.0%,70 - 79岁为12.0%,80岁及以上为29.0%。女性中,EDS的年龄特异性患病率在20 - 29岁为14.7%,30 - 39岁为8.7%,40 - 49岁为15.0%,50 - 59岁为16.0%,60 - 69岁为12.6%,70 - 79岁为13.2%,80岁及以上为17.0%。男性EDS的总体标准化患病率为10.4%(95%置信区间,9.7 - 11.2),女性为13.6%(95%置信区间,12.8 - 14.4)。

结论

EDS的患病率随年龄增长而增加,影响了约三分之一的80岁及以上人群。由于EDS与老年人群中较差的健康结果相关,这些发现表明常规筛查可能有助于对这些个体进行持续的健康评估。总体而言,超过十分之一的澳大利亚成年人口患有EDS,这表明可能存在潜在的睡眠病理状况。

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