Mäkelä J P, Hari R, Leinonen L
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland.
Electroencephalogr Clin Neurophysiol. 1988 May;69(5):423-30. doi: 10.1016/0013-4694(88)90064-8.
We recorded evoked magnetic fields from the human auditory cortex to noise/square wave sequences. Two prominent deflections were observed: one 100 msec after the noise onset (N100m) and another 100 msec after the noise/square wave transition (N100m'). The amplitude of N100m' increased with decrease in square wave frequency from 2 kHz to 0.125 kHz and with increase in square wave duration from 4 msec to 200 msec. The latency of N100m' was on the average 23 msec longer for noise durations of 60 msec than 310 msec, whereas the amplitude of N100m' did not change. Increase in interstimulus interval from 1.1 to 8.8 sec enhanced the amplitude of N100m significantly more than that of N100m'. The small interaction between N100m and N100m' and their different recovery cycles suggest that different activation patterns underlie these two 100 msec responses at the auditory cortex.
我们记录了人类听觉皮层对噪声/方波序列的诱发磁场。观察到两个明显的偏转：一个在噪声开始后100毫秒（N100m），另一个在噪声/方波转换后100毫秒（N100m'）。N100m'的幅度随着方波频率从2千赫兹降低到0.125千赫兹以及方波持续时间从4毫秒增加到200毫秒而增加。对于60毫秒的噪声持续时间，N100m'的潜伏期平均比方波持续时间为310毫秒时要长23毫秒，而N100m'的幅度没有变化。刺激间隔从1.1秒增加到8.8秒时，N100m幅度的增强明显大于N100m'。N100m和N100m'之间的微小相互作用以及它们不同的恢复周期表明，这两个在听觉皮层的100毫秒反应是由不同的激活模式所引起的。
