Salehi Rezvanie, Samadikhah Jahanbakhsh, Azarfarin Rasul, Goldust Mohamad
Dapartment of Cardiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Dapartment of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Pak J Biol Sci. 2013 Dec 15;16(24):1936-42. doi: 10.3923/pjbs.2013.1936.1942.
Evaluating left atrium volume is a good way to estimate prognosis in acute myocardial infarction patients because it indicates to time and severity of diastolic dysfunction and longer-term results of acute myocardial infarction. The present study aims at evaluating the effect of left atrium volume on patients' prognosis following acute myocardial infarction. This is a cohort study conducted on 100 patients who were admitted with acute myocardial infarction. They were studied for 9 months and their one-month mortality rate was evaluated. The patients were studied considering demographic factors, risk factors, mechanical and arrhythmic complications and echocardiography indexes such as systolic and diastolic functions and left atrium volume. It was seen that mortality (27.3%, 6.22) in patients with atrium index > 32 mL m(-2) is more than cases with lower atrium index (1.3%, 1.78) (p = 0.001). There was not any meaningful difference in mortality rate of the patients considering age and gender (p > 0.05). This study indicated to lack of any meaningful difference in patients' mortality rate in terms of hypertension, diabetes, smoking and dyslipidemia. But, mortality rate was significantly higher in MI as a result of elevated-ST, diastolic dysfunction, restrictive pattern, ejection fraction of left atrium < 40%, left atrium volume index > 32 mL m(-2). High volume left atrium independently refers to bad prognosis in patients with acute myocardial infarction which is confirmed with outcome clinical predictors and common echocardiography indexes even following modification.
评估左心房容积是估计急性心肌梗死患者预后的一个好方法，因为它可提示舒张功能障碍的时间和严重程度以及急性心肌梗死的长期结果。本研究旨在评估左心房容积对急性心肌梗死后患者预后的影响。这是一项针对100例急性心肌梗死入院患者的队列研究。对他们进行了9个月的研究，并评估了他们的1个月死亡率。研究患者时考虑了人口统计学因素、危险因素、机械和心律失常并发症以及超声心动图指标，如收缩和舒张功能以及左心房容积。结果发现，心房指数>32 mL m(-2)的患者死亡率（27.3%，6.22）高于心房指数较低的患者（1.3%，1.78）（p = 0.001）。考虑年龄和性别时，患者的死亡率没有任何显著差异（p>0.05）。本研究表明，在高血压、糖尿病、吸烟和血脂异常方面，患者的死亡率没有任何显著差异。但是，由于ST段抬高、舒张功能障碍、限制性模式、左心房射血分数<40%、左心房容积指数>32 mL m(-2)，心肌梗死患者的死亡率显著更高。左心房容积增大独立提示急性心肌梗死患者预后不良，这在经过校正后仍得到临床预后预测指标和常见超声心动图指标的证实。
