Teyssier C, Fillol R, Abdoul-Carime H, Farizon B, Farizon M, Märk T D
Institut de Physique Nucléaire de Lyon, UMR5822, Université Lyon 1, F-69622, Villeurbanne, France; Université de Lyon, F-69003, Lyon, France; and CNRS/IN2P3, F-69622, Villeurbanne, France.
Institut für Ionenphysik und Angewandte Physik, Leopold Franzens Universität Innsbruck, Technikerstrasse 25, A-6020 Innsbruck, Austria.
Rev Sci Instrum. 2014 Jan;85(1):015118. doi: 10.1063/1.4863015.
A new tandem mass spectrometry (MS/MS) method based on time of flight measurements performed on an event-by-event detection technique is presented. This "correlated ion and neutral time of flight" method allows to explore Collision Induced Dissociation (CID) fragmentation processes by directly identifying not only all ions and neutral fragments produced but also their arrival time correlations within each single fragmentation event from a dissociating molecular ion. This constitutes a new step in the characterization of molecular ions. The method will be illustrated here for a prototypical case involving CID of protonated water clusters H(+)(H2O)n = 1-5 upon collisions with argon atoms.
本文提出了一种基于飞行时间测量的新串联质谱（MS/MS）方法，该方法采用逐个事件检测技术。这种“相关离子与中性粒子飞行时间”方法不仅能直接识别解离分子离子在每个单分子碎裂事件中产生的所有离子和中性碎片，还能识别它们的到达时间相关性，从而有助于探索碰撞诱导解离（CID）碎裂过程。这是分子离子表征方面的一个新进展。本文将以质子化水团簇H⁺(H₂O)ₙ（n = 1 - 5）与氩原子碰撞时的CID这一典型案例对该方法进行说明。
