在土耳其西黑海地区一个严重缺碘地区实施强制性食盐碘化计划6年后，学龄儿童甲状腺肿和甲状腺功能减退的患病率。

The prevalence of goiter and hypothyroidism among school children 6 years after introduction of a mandatory salt iodination program in a severely iodine-deficient area of the West Black Sea region of Turkey.

作者信息

Uzun Hakan, Gozkaya Sercin, Yesildal Nuray, Okur Mesut, Arslanoglu İlknur, Kocabay Kenan, Senses Dursun A

机构信息

Department of Pediatrics, Duzce University School of Medicine, Duzce, Turkey

Department of Pediatrics, Duzce University School of Medicine, Duzce, Turkey.

出版信息

J Trop Pediatr. 2014 Aug;60(4):318-21. doi: 10.1093/tropej/fmu004. Epub 2014 Feb 10.

DOI:10.1093/tropej/fmu004

PMID:24519672

Abstract

The objective of the current study was to determine the prevalence and the degree of iodine deficiency after mandatory salt iodization in Yığılca's school-aged children. A total of 806 school children aged 6-19 years were evaluated. The prevalence of goiter in children aged 6-12 and 13-19 years was 20.3 and 23.8%, respectively. The prevalence of hypothyroidism in children aged 6-12 and 13-19 years was 10.4 and 18.9%, respectively. The median serum free tetraiodothyronine (fT4) levels in children aged 6-12 and 13-19-years were 1.16 ng/dL and 0.91 ng/dL, respectively. The median urinary iodine concentration levels in children aged 6-12 and 13-19 years were 83 µg/l and 78 µg/l, respectively. The frequency of autoimmune thyroid disease was 2.1% in Yığılca's SAC. Goiter and iodine deficiency problems remain in rural areas of the West Black Sea Region of Turkey.

摘要

本研究的目的是确定在伊吉尔贾地区强制推行食盐加碘后学龄儿童碘缺乏的患病率及程度。共评估了806名6至19岁的学童。6至12岁和13至19岁儿童的甲状腺肿患病率分别为20.3%和23.8%。6至12岁和13至19岁儿童的甲状腺功能减退患病率分别为10.4%和18.9%。6至12岁和13至19岁儿童的血清游离甲状腺素（fT4）水平中位数分别为1.16 ng/dL和0.91 ng/dL。6至12岁和13至19岁儿童的尿碘浓度水平中位数分别为83 µg/l和78 µg/l。伊吉尔贾地区学龄儿童自身免疫性甲状腺疾病的发生率为2.1%。土耳其黑海西部地区农村地区仍存在甲状腺肿和碘缺乏问题。