Lee Hsun-Hwa, Hung Shih-Han, Tseng Te-Ming, Lin Yun-Ho, Cheng Ju-Chuan
Department of Neurology, Taipei Medical University-Shuang Ho Hospital, Taipei, Taiwan, R.O.C.
Department of Otolaryngology, Taipei Medical University Hospital, Taipei, Taiwan, R.O.C. ; Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei, Taiwan, R.O.C.
Oncol Lett. 2014 Mar;7(3):778-780. doi: 10.3892/ol.2014.1796. Epub 2014 Jan 14.
Primary pituitary gland cancer is extremely rare. The current study presents the case of a patient diagnosed with pituitary cancer three months after completing surgery and post-operative chemoradiotherapy for hypopharyngeal cancer. In this report we discuss 57-year-old patient who presented with diplopia and ptosis four months following the completion of treatment for hypopharyngeal cancer. A poorly-differentiated pituitary carcinoma was located. Despite aggressive treatment and surgical excision with postoperative chemoradiotherapy, the disease progressed rapidly and the patient succumbed due to multiple metastases and organ failure. This case report indicates a possible correlation between irradiation and the development of pituitary cancer.
原发性垂体癌极为罕见。本研究报告了一例下咽癌患者在完成手术及术后放化疗三个月后被诊断为垂体癌的病例。在本报告中,我们讨论了一名57岁的患者,该患者在完成下咽癌治疗四个月后出现复视和上睑下垂。发现了一例低分化垂体癌。尽管进行了积极治疗并手术切除,术后还进行了放化疗,但疾病进展迅速,患者因多处转移和器官衰竭而死亡。本病例报告表明放疗与垂体癌的发生之间可能存在关联。