Department of Urology, Hospital de Viladecans , Viladecans, Barcelona, Spain .
J Endourol. 2014 Jul;28(7):841-5. doi: 10.1089/end.2013.0715. Epub 2014 Mar 31.
Purpose: To analyze the efficacy and safety of vaporization of the prostate (VP) with the 150-W thulium:yttrium-aluminum-garnet (Tm:YAG) laser.
In a prospective series of 55 patients with small- and medium-size prostates undergoing major outpatient surgery (MOS), the primary objectives were to analyze changes in maximum flow (Qmax) and International Prostate Symptom Score (IPSS) after 6 months. Immediate (<30 days) and late (>30 days) complications were subsequently recorded.
An increase in mean Qmax of 9.33 mL/s (95% confidence interval [CI] of the mean difference 6.73-11.93; P<0.001) was recorded, and mean IPSS was reduced by 16.88 points (95% CI 14.22-19.54; P<0.001). The immediate complications recorded were acute urinary retention (one patient), urinary tract infection without fever (two patients), and macroscopic hematuria (two patients). The only late complication observed was bladder neck sclerosis (one patient).
After 6 months, VP with 150-W Tm:YAG presents promising results in the clinical improvement of patients with small- and medium-size prostates. Its complication rate is low and it offers excellent hemostasis. The data from our study provide the basis for the design of clinical trials to compare this technique with other procedures.
分析 150W 铥:钇铝石榴石(Tm:YAG)激光前列腺汽化术(VP)的疗效和安全性。
在一项前瞻性的 55 例小中型前列腺患者接受主要门诊手术(MOS)的系列研究中,主要目标是分析术后 6 个月最大尿流率(Qmax)和国际前列腺症状评分(IPSS)的变化。随后记录即刻(<30 天)和迟发(>30 天)并发症。
平均 Qmax 增加 9.33mL/s(95%可信区间[均值差]为 6.73-11.93;P<0.001),平均 IPSS 降低 16.88 分(95%可信区间为 14.22-19.54;P<0.001)。记录到的即刻并发症有急性尿潴留(1 例)、无发热的尿路感染(2 例)和肉眼血尿(2 例)。唯一观察到的迟发并发症是膀胱颈硬化(1 例)。
150W Tm:YAG 的 VP 术后 6 个月在改善小中型前列腺患者的临床症状方面具有良好的效果。其并发症发生率低,止血效果极佳。我们的研究数据为设计临床试验以比较该技术与其他手术提供了依据。