Djukanovic Bosko P, Micovic Slobodan, Stojanovic Ivan, Unic-Stojanovic Dragana, Birovljev Sinisa, Vukovic Petar M
Department of Cardiac surgery, Dedinje Cardiovascular Institute, Belgrade, Serbia.
Congenit Heart Dis. 2014 Sep-Oct;9(5):433-7. doi: 10.1111/chd.12164. Epub 2014 Feb 13.
Surgical closure of patent ductus arteriosus (PDA) is still required in selected adult patients. We analyzed the morphology of the anomaly and coexisting pathological findings in adult patients who were recently referred to our institute for surgical PDA repair.
Six adult PDA patients who were not considered candidates for percutaneous closure underwent surgical PDA correction. In three patients with isolated PDA, computed tomographic scan revealed short, wide, and distorted ductus. In the remainder three patients, concomitant heart or aortic disease was found. Transpulmonary approach under total cardiopulmonary bypass or hypothermic circulatory arrest was performed.
In all patients, a Dacron patch was used to close the duct. The balloon occlusion technique with normothermic cardiopulmonary bypass was performed in four patients. In one of these patients, the balloon occlusion was not feasible because of unfavorable ductal anatomy, and PDA was closed in short hypothermic circulatory arrest. In two patients with aortic aneurysm, PDA closure and aortic reconstruction were performed in deep hypothermic circulatory arrest. No significant complications occurred during postoperative course. After the mean follow-up period of 48 months, neither ductal reopening nor aneurysmal degeneration of remnant ductal tissue was found.
Surgical PDA closure in adults remains the treatment of choice in wide, deformed PDAs unsuitable for percutaneous closure and PDAs associated with surgical aortic or heart disease.
部分成年患者仍需通过手术闭合动脉导管未闭(PDA)。我们分析了近期转诊至我院接受PDA手术修复的成年患者的异常形态及并存的病理表现。
6例不适合经皮闭合的成年PDA患者接受了PDA手术矫正。3例单纯PDA患者的计算机断层扫描显示导管短、宽且扭曲。其余3例患者合并有心脏或主动脉疾病。在全心肺转流或低温循环停搏下采用经肺途径进行手术。
所有患者均使用涤纶补片闭合导管。4例患者在常温心肺转流下行球囊封堵技术。其中1例患者因导管解剖结构不佳,球囊封堵不可行,在短时间低温循环停搏下闭合PDA。2例合并主动脉瘤的患者在深度低温循环停搏下进行PDA闭合和主动脉重建。术后过程中未发生明显并发症。平均随访48个月后,未发现导管重新开放或残留导管组织的动脉瘤样退变。
对于不适合经皮闭合的宽而畸形的PDA以及与主动脉或心脏手术相关的PDA,成年患者的手术闭合仍是首选治疗方法。