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Re: enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated salmonella carrying a plasmid co-expressing p53 gene and MDM2 siRNA.

作者信息

Atala Anthony

出版信息

J Urol. 2014 Mar;191(3):866-7. doi: 10.1016/j.juro.2013.11.037. Epub 2013 Nov 23.

DOI:10.1016/j.juro.2013.11.037
PMID:24522076
Abstract
摘要

相似文献

1
Re: enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated salmonella carrying a plasmid co-expressing p53 gene and MDM2 siRNA.
J Urol. 2014 Mar;191(3):866-7. doi: 10.1016/j.juro.2013.11.037. Epub 2013 Nov 23.
2
Enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated Salmonella carrying a plasmid co-expressing p53 gene and mdm2 siRNA.携带共表达 p53 基因和 mdm2siRNA 质粒的减毒沙门氏菌转染增强顺铂对荷瘤小鼠前列腺癌的治疗效果。
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Synergistic suppression of prostatic cancer cells by coexpression of both murine double minute 2 small interfering RNA and wild-type p53 gene in vitro and in vivo.体内外共表达鼠双微体 2 小干扰 RNA 和野生型 p53 基因对前列腺癌细胞的协同抑制作用。
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4
Murine double minute 2 siRNA and wild-type p53 gene therapy interact positively with zinc on prostate tumours in vitro and in vivo.鼠双微体 2 短发夹 RNA 与野生型 p53 基因治疗在体外和体内与锌相互作用正向影响前列腺肿瘤。
Eur J Cancer. 2014 Apr;50(6):1184-94. doi: 10.1016/j.ejca.2013.12.027. Epub 2014 Jan 18.
5
Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival.p53(R172L)的前列腺特异性表达以不同方式调节p21、Bax和mdm2,从而抑制前列腺癌进展并延长生存期。
Mol Cancer Res. 2003 Dec;1(14):1036-47.
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Experimental therapy of human prostate cancer by inhibiting MDM2 expression with novel mixed-backbone antisense oligonucleotides: in vitro and in vivo activities and mechanisms.用新型混合骨架反义寡核苷酸抑制MDM2表达对人前列腺癌进行实验性治疗:体内外活性及作用机制
Prostate. 2003 Feb 15;54(3):194-205. doi: 10.1002/pros.10187.
7
Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer.腺病毒介导的p53基因疗法与化疗联合用于治疗人类头颈癌、卵巢癌、前列腺癌和乳腺癌时,疗效更佳。
Cancer Chemother Pharmacol. 1999;44(2):143-51. doi: 10.1007/s002800050959.
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MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner.MDM2抑制以p53依赖的方式使前列腺癌细胞对雄激素剥夺和放疗敏感。
Neoplasia. 2016 Apr;18(4):213-22. doi: 10.1016/j.neo.2016.01.006.
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Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances the sensitivity to cisplatin.
Biochem Biophys Res Commun. 2006 Jan 6;339(1):71-8. doi: 10.1016/j.bbrc.2005.10.181. Epub 2005 Nov 8.
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Phlda3, a urine-detectable protein, causes p53 accumulation in renal tubular cells injured by cisplatin.Phlda3,一种尿可检测蛋白,可导致顺铂损伤的肾小管细胞中 p53 积聚。
Cell Biol Toxicol. 2015 Apr;31(2):121-30. doi: 10.1007/s10565-015-9299-4. Epub 2015 Mar 26.

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