卡麦角林治疗巨大泌乳素瘤后桥脑疝入颅底。
Pons herniation into skull base after cabergoline therapy of giant prolactinoma.
作者信息
Moles Herbera Jesús, Rivero Celada David, Montejo Gañan Inmaculada, Fustero de Miguel David, Fuentes Uliaque Carlos, Vela Marín Ana Carmen
机构信息
Department of Neurosurgery, Miguel Servet University Hospital, 1-3 Isabel la Católica Av., 50009, Zaragoza, Spain,
出版信息
Pituitary. 2015 Feb;18(1):68-71. doi: 10.1007/s11102-014-0558-9.
INTRODUCTION
Pons herniation after cabergoline therapy for giant prolactinoma is a complication not documented in literature.
CASE REPORT
We report a medium aged patient who developed secondary hemiparesis after 18 months of medical treatment. MRI revealed pons herniation into the clivus. There was improvement with conservative treatment. Secuencial MRIs are presented showing the tumor at the moment of the diagnosis, tumor shrinkage and pons herniation.
DISCUSSION
Some studies have shown that a significant and rapid tumor shrinkage resulting from treatment with cabergoline can occur and it is thought that some complications are related with this tumor regression, as in the presented case.
引言
卡麦角林治疗巨大泌乳素瘤后发生脑桥疝是文献中未记载的一种并发症。
病例报告
我们报告一名中年患者，在接受药物治疗18个月后出现继发性偏瘫。磁共振成像（MRI）显示脑桥疝入斜坡。保守治疗后病情有所改善。呈现了系列MRI图像，显示诊断时的肿瘤、肿瘤缩小及脑桥疝情况。
讨论
一些研究表明，卡麦角林治疗可导致肿瘤显著快速缩小，并且认为一些并发症与这种肿瘤消退有关，如本病例所示。
Zotero 插件