Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee.
Clin Anat. 2014 Apr;27(3):463-6. doi: 10.1002/ca.22384. Epub 2014 Feb 12.
Age-associated changes to aortic anatomy and physiology have an effect on hemodynamics and play a large role in the genesis of cardiovascular pathologies including atherosclerosis, congestive heart failure, and aortic aneurysm. Despite their recognized role in hemodynamics, the complete mechanism for aortic aging is still not clear and their full effects on cardiovascular pathologies are unknown. This article serves as a review of the normal anatomy of the human aorta and its known age-associated changes.
年龄相关的主动脉解剖和生理学变化会影响血液动力学,并在包括动脉粥样硬化、充血性心力衰竭和主动脉瘤在内的心血管疾病的发生中起重要作用。尽管它们在血液动力学中的作用已得到认可,但主动脉老化的完整机制仍不清楚,它们对心血管疾病的全部影响也尚不清楚。本文旨在回顾人体主动脉的正常解剖结构及其已知的与年龄相关的变化。