Conte C C, Petrelli N J, Stulc J, Herrera L, Mittelman A
Department of Surgical Oncology, Roswell Park Memorial Institute, Buffalo, New York 14263.
Surg Gynecol Obstet. 1988 May;166(5):451-3.
Sixteen instances of adenocarcinoma of the appendix treated at Roswell Park Memorial Institute between 1964 and 1986 were reviewed. Thirteen of 15 were mucinous and ten were well differentiated. Synchronous metastases were present in 11 patients, with carcinomatosis being the most common pattern of metastases (nine patients). Seven of eight women had ovarian metastases. Nine of the 11 patients with metastatic disease presented with complaints referrable to the metastatic site. The five year survival rate was 50 per cent in the eight patients who underwent right hemicolectomy and 25 per cent in the four patients who underwent appendectomy. The data from this review support right hemicolectomy as the treatment of choice for adenocarcinoma of the appendix. The prolonged survival time of patients with metastatic disease and the symptomatic nature of that disease support the application of palliative oophorectomy in patients with ovarian metastases.
回顾了1964年至1986年间在罗斯威尔公园纪念研究所接受治疗的16例阑尾腺癌病例。15例中有13例为黏液性，10例分化良好。11例患者出现同步转移，癌性腹膜炎是最常见的转移模式（9例患者）。8名女性中有7名发生卵巢转移。11例转移性疾病患者中有9例出现与转移部位相关的症状。接受右半结肠切除术的8例患者的五年生存率为50%，接受阑尾切除术的4例患者的五年生存率为25%。本综述的数据支持右半结肠切除术作为阑尾腺癌的首选治疗方法。转移性疾病患者延长的生存时间以及该疾病的症状性质支持对卵巢转移患者进行姑息性卵巢切除术。
