Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, PR China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, PR China.
Marine Drugs Research Center, College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, PR China.
Fitoterapia. 2014 Apr;94:108-13. doi: 10.1016/j.fitote.2014.02.001. Epub 2014 Feb 10.
Four new limonoids, named granatumins V-Y (1-4), belonging to the small group of limonoids with a C1-C29 oxygen bridge and a ∆(8,30) double bond, were isolated from the seeds of an Indian mangrove, Xylocarpus granatum, collected in the swamp of Krishna estuary, Andhra Pradesh. The constitutions and absolute configurations of these compounds were established by extensive NMR investigations, single-crystal X-ray crystallography using Cu Kα radiation, and by the comparison of circular dichroism spectrum.
从印度红树林 Xylocarpus granatum 的种子中分离得到了四种新的 Limonoids,分别命名为 granatumins V-Y(1-4),它们属于具有 C1-C29 氧桥和 ∆(8,30)双键的 Limonoids 小类。这些化合物的结构和绝对构型是通过广泛的 NMR 研究、单晶 X 射线晶体学(使用 Cu Kα 辐射)和圆二色光谱的比较确定的。