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[激肽在颅脑损伤发病机制中的作用及抗蛋白水解纠正疗法的验证]

[Role of kinins in the pathogenesis of craniocerebral injury and the validation of corrective antiproteolytic therapy].

作者信息

Valeev E K, Tsibul'kin A P, Raĭzman S M

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1988 Jan-Feb(1):7-11.

PMID:2452541
Abstract

The role of the kinin system in the development of extra- and intracerebral complications in the acute period of severe craniocerebral trauma was studied from complex clinical and biochemical examination. The authors substantiate the expediency of applying corrective antiproteolytic therapy, in which case the predominant trend of its action--inhibition of kinin production in the vascular bed or on the tissue level--must be taken into account. The time, duration, and methods of Contrykal administration were developed.

摘要

通过综合临床和生化检查,研究了激肽系统在重型颅脑创伤急性期脑外和脑内并发症发生发展中的作用。作者证实了应用纠正性抗蛋白水解疗法的合理性,在这种情况下,必须考虑其作用的主要趋势——抑制血管床或组织水平上的激肽产生。制定了抑肽酶的给药时间、持续时间和方法。

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[Role of kinins in the pathogenesis of craniocerebral injury and the validation of corrective antiproteolytic therapy].[激肽在颅脑损伤发病机制中的作用及抗蛋白水解纠正疗法的验证]
Zh Vopr Neirokhir Im N N Burdenko. 1988 Jan-Feb(1):7-11.
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